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DNV/MNV detection #246

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Bioinfowangm opened this issue Feb 20, 2025 · 0 comments
Open

DNV/MNV detection #246

Bioinfowangm opened this issue Feb 20, 2025 · 0 comments

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@Bioinfowangm
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Hi there,

I have been using Strelka2 for somatic mutation call. For di-nucleotide variants, such as CC>TT mutations which can be frequent in UV exposed cancers, it seems that these mutations were treated as multiple separate C>T variants. I wonder if there is a way to output these DNVs (and MNVs) as a single mutation, rather than multiple different variants. Thanks!

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