Bucket of Blood Street is located off U.S. Route 66 in the Old Downtown district of Holbrook, Arizona. Bucket of Blood Street is one block south of the historical Santa Fe Railroad station on Navajo Road that was built in 1882. Holbrook was founded in the 1880s as a railroad stop. At the time, the desert town was mainly populated by ranchers, outlaws, cowboys and cattle rustlers, and was known for its gun fights. Holbrook had a reputation as a "town too tough for women and churches".