About: De Kimpe aziridine synthesis
The De Kimpe azirdine synthesis is a name reaction of organic chemistry, for the generation of aziridines by the reaction of α-chloroimines with nucleophiles such as hydride, cyanide, or Grignard reagents. The De Kimpe aziridine synthesis is suitable for both aldimines and ketamines, particularly those with two alkyl substituents on the α-carbon (Thorpe-Ingold effect).
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