Inyathi High School (formerly Inyathi Mission and Inyathi Secondary School) is a boarding co-educational secondary school in Inyathi, Zimbabwe. It was established in 1889, making it the oldest formal educational institution in Zimbabwe. Along with in Plumtree and (formerly Hope Fountain Mission) in Bulawayo, Inyathi High School is privately owned by the United Congregational Church of Southern Africa (UCCSA) which is itself an offshoot of the London Missionary Society (LMS).