About: ORF6

An Entity of Type: protein, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

ORF6 is a gene that encodes a viral accessory protein in coronaviruses of the subgenus Sarbecovirus, including SARS-CoV and SARS-CoV-2. It is not present in MERS-CoV. It is thought to reduce the immune system response to viral infection through interferon antagonism.

Property	Value
dbo:abstract	ORF6 هو جين يشفر بروتينا ملحقا في الجُنيس فيروسات كورونا البائية السارسية (Sarbecovirus) من فيروسات كورونا والذي يشمل سارس-كوف وسارس-كوف-2. وهو غير متواجد في ميرس-كوف. يُعتقد أنه يُخفض استجابة الجهاز المناعي عند الإصابة بالفيروس عبر مناهضة الإنترفيرون. (ar) ORF6 is a gene that encodes a viral accessory protein in coronaviruses of the subgenus Sarbecovirus, including SARS-CoV and SARS-CoV-2. It is not present in MERS-CoV. It is thought to reduce the immune system response to viral infection through interferon antagonism. (en)
dbo:symbol	bCoV_NS6
dbo:wikiPageID	68816359 (xsd:integer)
dbo:wikiPageLength	7199 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID	1059590082 (xsd:integer)
dbo:wikiPageWikiLink	dbr:Protein-protein_interaction dbr:Sarbecovirus dbr:Endoplasmic_reticulum dbr:C-terminal dbr:Cytosol dbr:Vesicle_(biology_and_chemistry) dbr:Virion dbr:ORF7a dbr:ORF7b dbr:RAE1 dbr:Signal_peptide dbr:Coronavirus dbr:Coronavirus_membrane_protein dbr:Coronavirus_nucleocapsid_protein dbr:SARS-CoV dbr:SARS-CoV-2 dbr:STAT_protein dbr:Essential_gene dbr:Viral_structural_protein dbr:Gene dbr:Amphipathic dbr:MERS-CoV dbr:Karyopherin dbr:Alpha_helix dbc:Coronavirus_proteins dbr:Cell_membrane dbr:Golgi_apparatus dbr:Transcription_factor dbr:Recombinant_virus dbr:Viral_replication dbr:Transmembrane_protein dbr:Chemical_polarity dbr:Autophagosome dbr:Interferon dbr:ORF8 dbr:ORF9b dbr:Sequence_conservation dbr:Virus-like_particle dbr:Immune_system dbr:Immunomodulation dbr:Subcellular_localization dbr:Lysosome dbr:NUP98 dbr:Subgenus dbr:Murine_hepatitis_virus dbr:Protein_trafficking dbr:Viral_accessory_protein dbr:Host_cell dbr:Amino_acid_residue dbr:5' dbr:Immune_evasion dbr:N-terminal dbr:Nuclear_import dbr:Sequence_identity
dbp:interpro	IPR022736 (en)
dbp:name	Betacoronavirus NS6 protein (en)
dbp:pfam	PF12133 (en)
dbp:symbol	bCoV_NS6 (en)
dbp:wikiPageUsesTemplate	dbt:Infobox_protein_family dbt:Reflist dbt:Short_description dbt:Coronavirus_genomes dbt:Viral_proteins
dcterms:subject	dbc:Coronavirus_proteins
rdf:type	owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8054 dbo:Protein
rdfs:comment	ORF6 هو جين يشفر بروتينا ملحقا في الجُنيس فيروسات كورونا البائية السارسية (Sarbecovirus) من فيروسات كورونا والذي يشمل سارس-كوف وسارس-كوف-2. وهو غير متواجد في ميرس-كوف. يُعتقد أنه يُخفض استجابة الجهاز المناعي عند الإصابة بالفيروس عبر مناهضة الإنترفيرون. (ar) ORF6 is a gene that encodes a viral accessory protein in coronaviruses of the subgenus Sarbecovirus, including SARS-CoV and SARS-CoV-2. It is not present in MERS-CoV. It is thought to reduce the immune system response to viral infection through interferon antagonism. (en)
rdfs:label	ORF6 (ar) ORF6 (en)
owl:sameAs	wikidata:ORF6 dbpedia-ar:ORF6 https://global.dbpedia.org/id/G5CSh
prov:wasDerivedFrom	wikipedia-en:ORF6?oldid=1059590082&ns=0
foaf:isPrimaryTopicOf	wikipedia-en:ORF6
is dbo:wikiPageWikiLink of	dbr:SARS-related_coronavirus dbr:RaTG13 dbr:ORF8 dbr:ORF9b
is foaf:primaryTopic of	wikipedia-en:ORF6

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