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対立遺伝子 Allel Allel Аллели Alelo 等位基因 Alel Allele Allele Alelo Alelo 대립유전자 أليل (وراثة) Αλληλόμορφα Al·lel Allel Allel Alelo Alela Allèle Ailléil Алелі
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Allel – jedna z wersji genu. Allel najczęściej występuje w określonym locus na danym chromosomie homologicznym, jednak pojęcie to odnosi się także do genomu cytoplazmatycznego oraz prokariotycznego. Allele tego samego genu różnią się jednym lub kilkoma nukleotydami. Istnienie więcej niż jednej wersji danego genu określa się jako polimorfizm. Dzięki zdegenerowaniu kodu genetycznego tylko część tych różnic przekłada się na różnice w budowie kodowanych białek. Powoduje to zróżnicowanie właściwości cząsteczek białka kodowanego przez różne allele tego samego genu. الأليل أو الحليل أو البديل أو الداغش (بالإنجليزية: allele)‏ هو نسخة أو شكل بديل للجين أو موقع كروموسومي (عادة يتكون من مجموعة جينات). وللجين على الأقل نسختان أو شكلان بديلان. أحيانا قد ينتج عن ألألائل المختلفة المحتوية على اختلافات في الشفرة الوراثية خلات مختلفة (كلون الجلد أو العين). إلا أن الكثير من الاختلافات لا تؤدي إلا لاختلاف ظاهري طفيف أو معدوم. هذا وتعد كلمة أليل allele مُصَغَر كلمة allelomorph والتي كانت تستخدم في الأيام الأولى لعلم الوراثة من أجل وصف الصيغ المختلفة للجين التي تبينت من خلال الأنماط الظاهرية المختلفة. Un alelo o alelomorfo​ ​(del griego ἁλλήλως, lit. «de uno para con el otro») es cada una de las formas alternativas que puede tener un mismo gen y que se puede manifestar en modificaciones concretas de la función de éste (producen variaciones en características heredadas como, por ejemplo, el color de ojos o el grupo sanguíneo).​ Dado que la mayoría de los mamíferos son diploides, poseen dos juegos de cromosomas, uno de ellos procedente del padre y el otro de la madre. Cada par de alelos se ubica en igual locus o lugar del cromosoma. Die Desoxyribonukleinsäure (DNS oder DNA) an einem Genlokus, also an einer bestimmten Stelle eines bestimmten Chromosoms, kann zwischen Individuen einer Spezies variieren. Derartige Varianten eines Gens werden als Allele des Gens bezeichnet (von altgriechisch αλλήλων allélon „einander, gegenseitig“). Unterschiedliche Allele bewirken häufig unterschiedliche Ausprägungen des dem Gen entsprechenden Merkmals im Phänotyp des Individuums. Zum Beispiel kann es für ein Gen, das die Blütenfarbe bestimmt, ein Allel geben, das die Blüten rot, und ein anderes Allel, das sie weiß sein lässt. Die Existenz der Allele und ihre Weitergabe bei der Fortpflanzung erklärt die Vererbung individueller Merkmale und insbesondere die schon 1865 von Gregor Mendel entdeckten und nun nach ihm benannten Mendelschen Reg Алельні гени, алелі (від лат. allelos — протилежний) — парні гени, що займають одні й ті самі локуси гомологічних хромосом і визначають альтернативні взаємовиключні стани тієї самої ознаки. Трапляються в межах однієї популяції організмів та визначають різні фенотипи цих організмів. Τo αλληλόμορφo είναι μία από τις δύο ή περισσότερες μορφές ενός γονιδίου. Για παράδειγμα, η ομάδα αίματος ΑΒΟ ελέγχεται από το γονίδιο ΑΒΟ που έχει τρία κοινά αλληλόμορφα (ΙΑ, IΒ, i). Ένα άτομο κληρονομεί δύο αλληλόμορφα για κάθε γονίδιο, ένα από κάθε γονέα. Εάν τα δύο αλληλόμορφα είναι τα ίδια, το άτομο είναι για αυτό το γονίδιο. Εάν τα αλληλόμορφα είναι διαφορετικά, το άτομο είναι . Os alelos são as formas alternativas, gerados por mutações, de um mesmo gene. Estes, por sua vez, estão em posições específicas na extensão de um cromossomo ou locus gênico. Algumas vezes, alelos diferentes podem resultar em uma diferente característica fenotípica, como a pigmentação. Porém, a maioria das variações genéticas resultam em pouca ou nenhuma variação observável. Allel (egentligen allelomorf, av grekiskana al'lēlōn ’varandra’ och morphēʹ ’form’), eller genvariant, är en av flera alternativa versioner av en gen eller annan nukleotidsekvens. Ordet kommer av grekiskans allelomorph, annan form. Alleler är varianter av ärftliga anlag som bär den information i form av ritningar till RNA och protein som sammantaget bygger upp individen och ger den dess egenskaper. Hos människan kan olika alleler påverka till exempel hårfärg, ögonfärg eller blodgrupp. De flesta genetiska sjukdomar orsakas av recessiva alleler. Ibland kan sjukdomar orsakas av dominanta alleler. Alelo estas unu el nombraj alternativaj formoj de sama geno aŭ sama genetika lokuso (ĝenerale grupo de genoj). Ĝi estas la alternativa formo de geno por karaktero produktanta malsamajn efikojn. Foje malsamaj aleloj povas rezultigi malsamajn observeblajn fenotipajn trajtojn, kiel ekzemple malsama pigmentaĵo. Tamen, multaj genetikaj varioj rezultas en malgranda aŭ neniu observebla vario. Is éard atá in ailléil ceann de dhá chineál nó os a chionn de ghéin nó de lócas géiniteach (ar grúpa géinte é go minic). Uaireanta is iad na hailléilí is ciontach le tréithe feinitíopacha ar nós líocha. Achoimre ar "allamorf" atá ann, focal a úsáideadh tráth i gcúrsaí géineolaíochta chun cuntas a thabhairt ar shaghsanna difriúla de ghéin a aithníodh mar fheinitíopaí difriúla. Tagann sé ón ngas Ghréigise ἄλλος (allos) agus alius (eile) na Laidine, focail a thugann αλληλους (allelos) - "a chéile". 対立遺伝子(たいりついでんし、英: allele)とは、対立形質を規定する個々の遺伝子を指す。アレル, アリルと呼ばれることもある。 대립유전자(對立遺傳子, 영어: allele) 상동 염색체의 같은 위치에 존재하며, 같은 형질을 결정하는 유전자이다. 한 쌍의 대립유전자 조합에 의해 표현형이 결정된다. Un allèle (abréviation d'allélomorphe) est une version variable d'un même gène, c'est-à-dire une forme variée qui peut être distinguée par des variations de sa séquence nucléotidique. Il existe généralement quelques allèles pour chaque gène, mais certains gènes (par exemple ceux du CMH) possèdent plusieurs dizaines d'allèles. Les allèles d'une paire de chromosomes homologues peuvent être identiques, c'est l'homozygotie, ou différents, c'est l'hétérozygotie. Aleloak gene baten aldaerak dira. Bizidun diploideetan, aleloak kromosoma homologoetako leku berean (locus) kokatzen dira, eta karaktere bakoitza alelo pare batek kontrolatzen du. Alelo bikote honetako bat aitarengandik dator, eta bestea amarengandik. Esaterako, ilarraren haziaren kolorea kontrolatzen duen geneak bi alelo ditu: batek berde kolorea eragiten du, eta besteak kolore horia. Horrela, bi alelo horiekin (a1 eta a2) hiru konbinazio mota izan daitezke: Bestalde, fenotipoan agertzen den emaitzaren arabera honako sailkapen hau egin daiteke: Alela (allela, alelomorfa) je konkrétní forma genu. Každá alela může mít jednu nebo několikero forem. Gen je zodpovědný za znak (například za barvu očí), zatímco alela je zodpovědná za projev znaku (zda budou oči modré nebo hnědé). Alely se vyskytují v párech, základem je forma dominantní (A) a recesivní (a). Jednu alelu dědí jedinec po otci, druhou po matce. Která z nich se projeví fenotypicky, záleží na kombinaci páru alel v somatické buňce (AA, Aa, aa). 等位基因(allele)旧称對偶基因,是同源染色體内同一个基因座上的多种表现形式;其在细胞有絲分裂时的兩個染色體上的基因座是對應排列的,故细胞遺傳學裡稱其為等位。 在一個二倍體(每條染色體都有兩套)生物體裡,某個基因的基因型是由該基因座的等位基因所決定。在人的一對同源染色體内,等位基因分别來自父辈和母辈的遺傳,其基因型决定了生物的表現型。生物的表現型由一对等位基因的其中一个决定的,稱為顯性基因;而由两个决定的,则称为隐性基因。例如等位基因的一个突變,可产生癌基因,而兩个的突變或丢失,則可導致腫瘤抑制基因,或抑癌基因的突變。這些基因的改變是腫瘤發生的分子基礎。 Dalam genetika, alel (dari bahasa Belanda, allel, dibentuk dari kata bahasa Yunani, αλλήλων atau allélon, "saling berhadapan") merupakan bentuk-bentuk alternatif dari gen pada suatu lokus. Alel adalah sepasang gen yang memiliki pengaruh berlawanan. Alel terbentuk karena adanya variasi pada urutan basa nitrogen akibat peristiwa mutasi. Istilah ini muncul akibat penggunaan allelomorph oleh William Bateson pada buku karangannya Mendel's Principles of Heredity (1902). Un allele (dal Greco ἄλλος állos, "altro") è una delle diverse forme in cui può presentarsi un gene. L'insieme di tutti gli alleli per un particolare carattere costituisce la totalità delle informazioni genetiche che definiscono un gene. Un allele è una variazione della sequenza di nucleotidi che codifica la sintesi di un prodotto genico nello stesso punto (locus genico) su una lunga molecola di DNA. Due alleli possono differire per una sola coppia di basi oppure per diverse migliaia. Een allel is een bepaalde variant van een gen. Een gen codeert een bepaalde erfelijke eigenschap, waarbij verschillende versies van een gen min of meer verschillende gevolgen kunnen hebben voor die eigenschap van een organisme.Elke uitvoering van een gen wordt een allel (meervoud allelen) of mendeliaanse erffactor genoemd. Als een organisme voor een bepaald gen twee gelijke allelen heeft, is het organisme voor die eigenschap homozygoot. Als een organisme voor een gen twee verschillende allelen heeft, is het organisme heterozygoot voor een bepaalde eigenschap. Un al·lel (del grec. allḗlōn 'recíproc') és cadascuna de les formes alternatives que pot presentar un gen que ocupa el mateix lloc en un cromosoma determinat o en dos cromosomes homòlegs, i que expressa diferentment un mateix caràcter. Алле́ли (от греч. ἀλλήλων — друг друга, взаимно) — различные формы одного и того же гена, расположенные в одинаковых участках (локусах) гомологичных хромосом, определяют направление развития конкретного признака. В диплоидном организме может быть два одинаковых аллеля одного гена, в этом случае организм называется гомозиготным, или два разных, что приводит к гетерозиготному организму. Однако, несмотря на разнообразие взаимодействия аллелей, порой весьма сложных, все они подчиняются первому закону Менделя — закону единообразия гибридов первого поколения. An allele (UK: /ˈæliːl/, /əˈliːl/; US: /əˈliːl/; modern formation from Greek ἄλλος állos, "other") is a variation of the same sequence of nucleotides at the same place on a long DNA molecule, as described in leading textbooks on genetics and evolution. "The chromosomal or genomic location of a gene or any other genetic element is called a locus (plural: loci) and alternative DNA sequences at a locus are called alleles." The simplest alleles are single nucleotide polymorphisms (SNP). but they can also be insertions and deletions of up to several thousand base pairs.
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Eye color is an inherited trait influenced by more than one gene, including OCA2 and HERC2. The interaction of multiple genes—and the variation in these genes between individuals—help to determine a person's eye color phenotype. Eye color is influenced by pigmentation of the iris and the frequency-dependence of the light scattering by the turbid medium within the stroma of the iris.
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Dalam genetika, alel (dari bahasa Belanda, allel, dibentuk dari kata bahasa Yunani, αλλήλων atau allélon, "saling berhadapan") merupakan bentuk-bentuk alternatif dari gen pada suatu lokus. Alel adalah sepasang gen yang memiliki pengaruh berlawanan. Alel terbentuk karena adanya variasi pada urutan basa nitrogen akibat peristiwa mutasi. Istilah ini muncul akibat penggunaan allelomorph oleh William Bateson pada buku karangannya Mendel's Principles of Heredity (1902). Lokus dikatakan bersifat polimorfik apabila memiliki variasi alel dalam suatu populasi dan, sebaliknya, dikatakan bersifat monomorfik ("satu bentuk") apabila tidak memiliki variasi. Individu yang memiliki alel sama pada suatu lokus dikatakan memiliki genotipe yang homozigot sedangkan yang memiliki alel berbeda dikatakan heterozigot. Karena genotipe diekspresikan menjadi suatu fenotipe, alel dapat menyebabkan perbedaan penampilan di antara individu-individu dalam suatu populasi. Alela (allela, alelomorfa) je konkrétní forma genu. Každá alela může mít jednu nebo několikero forem. Gen je zodpovědný za znak (například za barvu očí), zatímco alela je zodpovědná za projev znaku (zda budou oči modré nebo hnědé). Alely se vyskytují v párech, základem je forma dominantní (A) a recesivní (a). Jednu alelu dědí jedinec po otci, druhou po matce. Která z nich se projeví fenotypicky, záleží na kombinaci páru alel v somatické buňce (AA, Aa, aa). Je-li alel na jednom lokusu více, může se jednat o genetický polymorfismus. Drobná, ale i třeba z hlediska struktury genu rozsáhlá mutace, která nemá za výsledek dostatečně odlišnou expresi genu, se za novou alelu nepovažuje. Obdobné je to s výskytem: Stejných alel musí být v populaci více než 1 %, jinak se nepovažují za genetický polymorfismus. Ten definuje skupiny, odlišuje jedince, dělí populace. Krajním případem je jednonukleotidový polymorfismus, kdy se alely liší pouze v jediném nukleotidu (u více než 1 % populace). Odhalovat tak malé změny v alelách je úkol molekulární genetiky. Místo genotypu a fenotypu se mluví o sekvencích DNA a odezvě organismu na molekulární úrovni (není vidět, ale dá se dokázat laboratorním testem). 対立遺伝子(たいりついでんし、英: allele)とは、対立形質を規定する個々の遺伝子を指す。アレル, アリルと呼ばれることもある。 Die Desoxyribonukleinsäure (DNS oder DNA) an einem Genlokus, also an einer bestimmten Stelle eines bestimmten Chromosoms, kann zwischen Individuen einer Spezies variieren. Derartige Varianten eines Gens werden als Allele des Gens bezeichnet (von altgriechisch αλλήλων allélon „einander, gegenseitig“). Unterschiedliche Allele bewirken häufig unterschiedliche Ausprägungen des dem Gen entsprechenden Merkmals im Phänotyp des Individuums. Zum Beispiel kann es für ein Gen, das die Blütenfarbe bestimmt, ein Allel geben, das die Blüten rot, und ein anderes Allel, das sie weiß sein lässt. Die Existenz der Allele und ihre Weitergabe bei der Fortpflanzung erklärt die Vererbung individueller Merkmale und insbesondere die schon 1865 von Gregor Mendel entdeckten und nun nach ihm benannten Mendelschen Regeln. Schädliche Allele bewirken Erbkrankheiten. – Die Erscheinung an sich heißt Allelie. Hat ein Gen mehr als zwei Allele, so spricht man von multipler Allelie. Allele können über lange Zeit unverändert vererbt werden oder durch Mutation neu entstehen. Die Auswirkungen der Allelie auf die Vererbung von genotypischen und vor allem von phänotypischen Eigenschaften sind so vielfältig, dass dieser Artikel nur das Grundmuster beschreiben kann. Die hier betrachteten Lebewesen sind Diplonten. Das heißt, sie produzieren Keimzellen, Gameten, mit einem einfachen Chromosomensatz, und alle übrigen, die ‚somatischen‘ Zellen haben zwei Chromosomensätze, je einen von den in der Befruchtung zur Zygote vereinigten Keimzellen. Insbesondere betrifft das Folgende den Menschen, da er zu den Diplonten gehört. الأليل أو الحليل أو البديل أو الداغش (بالإنجليزية: allele)‏ هو نسخة أو شكل بديل للجين أو موقع كروموسومي (عادة يتكون من مجموعة جينات). وللجين على الأقل نسختان أو شكلان بديلان. أحيانا قد ينتج عن ألألائل المختلفة المحتوية على اختلافات في الشفرة الوراثية خلات مختلفة (كلون الجلد أو العين). إلا أن الكثير من الاختلافات لا تؤدي إلا لاختلاف ظاهري طفيف أو معدوم. معظم الكائنات الحية متعددة الخلايا تحتوي على مجموعتين اثنتين من الكروموسومات، إذ ترث واحدة من الأب وواحدة من الأم، أي أنها . وتسمى هذه الكروموسومات بالكروموسومات المتماثلة. بما أن الكائنات الحية الضعفانية تحمل مجموعتين من الكروموسومات، هذا يعني أنها تحمل نسختين من كل جين (أي زوجاً من الألائل لكل جين). إن كان كلا الأليلان متطابقان، فالكائن الحامل لها يسمى زيجوت متماثل, ويصف بمتماثل الزيجوت. وإن كان الأليلان مختلفان، فالحامل لها هو زيجوت متباين ويصف بمتباين الزيجوت. إجمالاً يمتلك الأفراد المنتمون لتجمع أو نوع من الكائنات الحية عدة ألائل (نسخ مختلفة من الجينات) لكل موضع كروموسومي locus. يمكن قياس درجة التنوع الأليلي لموضع كروموسومي معين بعدد الألائل الموجودة، أو بالنسبة التي يشكلها متباينو الزيجوت من التجمع. هذا وتعد كلمة أليل allele مُصَغَر كلمة allelomorph والتي كانت تستخدم في الأيام الأولى لعلم الوراثة من أجل وصف الصيغ المختلفة للجين التي تبينت من خلال الأنماط الظاهرية المختلفة. Een allel is een bepaalde variant van een gen. Een gen codeert een bepaalde erfelijke eigenschap, waarbij verschillende versies van een gen min of meer verschillende gevolgen kunnen hebben voor die eigenschap van een organisme.Elke uitvoering van een gen wordt een allel (meervoud allelen) of mendeliaanse erffactor genoemd. Als een organisme voor een bepaald gen twee gelijke allelen heeft, is het organisme voor die eigenschap homozygoot. Als een organisme voor een gen twee verschillende allelen heeft, is het organisme heterozygoot voor een bepaalde eigenschap. Τo αλληλόμορφo είναι μία από τις δύο ή περισσότερες μορφές ενός γονιδίου. Για παράδειγμα, η ομάδα αίματος ΑΒΟ ελέγχεται από το γονίδιο ΑΒΟ που έχει τρία κοινά αλληλόμορφα (ΙΑ, IΒ, i). Ένα άτομο κληρονομεί δύο αλληλόμορφα για κάθε γονίδιο, ένα από κάθε γονέα. Εάν τα δύο αλληλόμορφα είναι τα ίδια, το άτομο είναι για αυτό το γονίδιο. Εάν τα αλληλόμορφα είναι διαφορετικά, το άτομο είναι . Για κάθε χαρακτηριστικό, οι διαθέτουν δύο αλληλόμορφα που βρίσκονται στην ίδια θέση των ομόλογων χρωμοσωμάτων. Το ζευγάρι των αλληλόμορφων συνιστά τον γονότυπο ενώ η έκφρασή τους συνιστά τον φαινότυπο. Συνήθως από τα δύο αλληλόμορφα, το ένα επικρατεί έναντι του άλλου και καθορίζει τον φαινότυπο. Αυτό το αλληλόμορφο ονομάζεται επικρατές και το άλλο υπολειπόμενο. Το επικρατές συνήθως το συμβολίζουμε με ένα κεφαλαίο γράμμα, ενώ το υπολειπόμενο με ένα μικρό. Αν "Α" είναι το επικρατές αλληλόμορφο που ελέγχει ένα χαρακτηριστικό, το υπολειπόμενο θα συμβολίζεται με "α". Οι δυνατοί γονότυποι από τον συνδυασμό των δύο αλληλόμορφων είναι τρεις (ΑΑ,Αα,αα) και οι δυνατοί φαινότυποι δύο (Α,α). Ο φαινότυπος Α εκφράζεται σε δύο περιπτώσεις, για γονότυπο ΑΑ και για γονότυπο Αα αφού το Α είναι επικρατές. Αντίθετα ο φαινότυπος α εκφράζεται μόνο όταν έχουμε γονότυπο αα. Υπάρχουν διαφορετικά μεγέθη αλληλόμορφων. Στο μικρότερο δυνατό μέγεθος ένα αλληλόμορφο μπορεί να είναι ένας (SNP). Στο μεγαλύτερο δυνατό μέγεθος, μπορεί να έχει μήκος έως και αρκετές χιλιάδες ζεύγη βάσεων. Τα περισσότερα αλληλόμορφα έχουν μικρή ή καμία παρατηρήσιμη επίδραση στη λειτουργία της πρωτεΐνης που κωδικοποιείται από ένα γονίδιο. Un allèle (abréviation d'allélomorphe) est une version variable d'un même gène, c'est-à-dire une forme variée qui peut être distinguée par des variations de sa séquence nucléotidique. Il existe généralement quelques allèles pour chaque gène, mais certains gènes (par exemple ceux du CMH) possèdent plusieurs dizaines d'allèles. Les allèles d'une paire de chromosomes homologues peuvent être identiques, c'est l'homozygotie, ou différents, c'est l'hétérozygotie. C'est ainsi qu'au sein d'une même espèce, le génome d'un individu est différent de celui d'un autre individu, c'est le polymorphisme génétique. Ce polymorphisme est également dû à l'apparition de mutations qui sont des variations de la séquence nucléotidique. Il peut donc exister dans les populations naturelles plusieurs séquences différentes d'ADN pour un même locus. Un alelo o alelomorfo​ ​(del griego ἁλλήλως, lit. «de uno para con el otro») es cada una de las formas alternativas que puede tener un mismo gen y que se puede manifestar en modificaciones concretas de la función de éste (producen variaciones en características heredadas como, por ejemplo, el color de ojos o el grupo sanguíneo).​ Dado que la mayoría de los mamíferos son diploides, poseen dos juegos de cromosomas, uno de ellos procedente del padre y el otro de la madre. Cada par de alelos se ubica en igual locus o lugar del cromosoma. Por alelo debe entenderse el valor de dominio que se otorga a un gen cuando rivaliza contra otro gen por la ocupación de posición final en los cromosomas durante la separación que se produce durante la meiosis celular. De ese valor de dominación del alelo procreador resultará la trasmisión, idéntica o distinta, de la copia o serie de copias del gen procreado. De acuerdo con esa potencia, un alelo puede ser dominante y expresarse en consecuencia en el hijo solamente con una de las copias procreadoras, por lo tanto si el padre o la madre lo poseen el cromosoma del hijo lo expresará siempre; o bien puede ser un alelo recesivo, por lo tanto se necesitarán dos copias del mismo gen, dos alelos, para que se exprese en el cromosoma procreado, esto es, deberá ser provisto al momento de la procreación por ambos progenitores. El concepto de alelo se entiende a partir de la palabra alelomorfo (en formas alelas) es decir, algo que se presenta de diversas formas dentro de una población de individuos. Aleloak gene baten aldaerak dira. Bizidun diploideetan, aleloak kromosoma homologoetako leku berean (locus) kokatzen dira, eta karaktere bakoitza alelo pare batek kontrolatzen du. Alelo bikote honetako bat aitarengandik dator, eta bestea amarengandik. Esaterako, ilarraren haziaren kolorea kontrolatzen duen geneak bi alelo ditu: batek berde kolorea eragiten du, eta besteak kolore horia. Horrela, bi alelo horiekin (a1 eta a2) hiru konbinazio mota izan daitezke: * Bi alelo a1 a1 (a1 aleloarekiko homozigotikoa) * Bi alelo a2 a2 (a2 aleloarekiko homozigotikoa) * Alelo bat a1 eta bestea a2 (heterozigotikoa: a1, a2) Bestalde, fenotipoan agertzen den emaitzaren arabera honako sailkapen hau egin daiteke: * Alelo gainartzaileak edo dominanteak: karaktere batentzat heterozigotoen fenotipoan, eta homozigotoenetan ere, agertzen direnak. Aurreko adibidea jarraituz, eta a1 ilarraren haziaren kolore horia eragiten duen aleloa bada (eta a2 kolore berdea sortzen duena), a1 a1 konbinazioak eta a1 a2-koak ere fenotipo horia izango dute (a1 alelo gainartzailea baita). * Alelo azpirakorrak edo errezesiboak: heterozigotoen fenotipoan ezkutatuta geratzen direnak, homozigotoetan bakarrik agertuz (aurreko adibidean, a2 aleloa). Alelo azpirakorra letra xehez (a, adibidez) idatzi ohi da, eta alelo gainartzailea, aldiz, letra larriz (A, esaterako). Adibide bat jartzearren, ilarraren haziaren kolorea mugatzen duen geneak bi ditu: batek hori kolorea eragiten du (A), eta besteak berdea (a). Kolore horia mugatzen duen aleloa (A) gainartzailea da, eta kolore berdea mugatzen duena (a) azpirakorra. Hortaz: * Genotipo homozigoto gainartzailea (AA) duen ilarrak hori kolorekoa izango du hazia. * Genotipo heterozigotoa duenak ere (Aa) hori kolorekoa izango du. * Genotipo homozigoto azpirakorra duenak (aa), aldiz, hazi berdea izanen du. Alelo estas unu el nombraj alternativaj formoj de sama geno aŭ sama genetika lokuso (ĝenerale grupo de genoj). Ĝi estas la alternativa formo de geno por karaktero produktanta malsamajn efikojn. Foje malsamaj aleloj povas rezultigi malsamajn observeblajn fenotipajn trajtojn, kiel ekzemple malsama pigmentaĵo. Tamen, multaj genetikaj varioj rezultas en malgranda aŭ neniu observebla vario. La plej multaj multĉelaj organismoj havas du arojn de kromosomoj, t.e., ili estas diploidaj. Tiuj kromosomoj estas referitaj kiel homologaj kromosomoj. Diploidaj organismoj havas unu kopion de ĉiu geno (kaj tial unu alelo) sur ĉiu kromosomo. Se ambaŭ aleloj estas la samaj, ili kaj la organismo estas homozigotaj, kaj la organismoj estas . Se la aleloj estas malsamaj, ili kaj la organismo estas heterozigotaj kaj la organismoj estas . Populacio aŭ specio de organismoj tipe inkludas multoblajn alelojn ĉe ĉiu lokuso inter diversaj individuoj. Alela vario ĉe lokuso estas mezurebla kiam la nombro da aleloj (polimorfismo) prezentiĝas, aŭ la proporcio de heterozigotoj en la populacio. Алле́ли (от греч. ἀλλήλων — друг друга, взаимно) — различные формы одного и того же гена, расположенные в одинаковых участках (локусах) гомологичных хромосом, определяют направление развития конкретного признака. В диплоидном организме может быть два одинаковых аллеля одного гена, в этом случае организм называется гомозиготным, или два разных, что приводит к гетерозиготному организму. Нормальные диплоидные соматические клетки содержат два аллеля одного гена (по числу гомологичных хромосом), а гаплоидные гаметы — лишь по одному аллелю каждого гена. Для признаков, подчиняющихся законам Менделя, можно рассматривать доминантные и рецессивные аллели. Если генотип особи содержит два разных аллеля (особь — гетерозигота), проявление признака зависит только от одного из них — доминантного. Рецессивный же аллель влияет на фенотип, только если находится в обеих хромосомах (особь — гомозигота). Таким образом, доминантный аллель подавляет рецессивный. В более сложных случаях наблюдаются другие типы аллельных взаимодействий (см. ниже). Однако, несмотря на разнообразие взаимодействия аллелей, порой весьма сложных, все они подчиняются первому закону Менделя — закону единообразия гибридов первого поколения. 대립유전자(對立遺傳子, 영어: allele) 상동 염색체의 같은 위치에 존재하며, 같은 형질을 결정하는 유전자이다. 한 쌍의 대립유전자 조합에 의해 표현형이 결정된다. Allel (egentligen allelomorf, av grekiskana al'lēlōn ’varandra’ och morphēʹ ’form’), eller genvariant, är en av flera alternativa versioner av en gen eller annan nukleotidsekvens. Ordet kommer av grekiskans allelomorph, annan form. Alleler är varianter av ärftliga anlag som bär den information i form av ritningar till RNA och protein som sammantaget bygger upp individen och ger den dess egenskaper. Hos människan kan olika alleler påverka till exempel hårfärg, ögonfärg eller blodgrupp. Nya alleler uppstår genom mutationer. I en population bär individerna på olika alleler för en viss gen vilket ger dem olika egenskaper. Ju större genetisk variation en population har desto större chans har den att överleva. Populationens sammanlagda allelsammansättning kallas för dess genpool. Alleler som ökar individens fitness (anpassning till omgivande miljön) tenderar till att öka i frekvens i kommande generationer och således förändra genpoolen för populationen på sikt. Människans 23 kromosompar bär på dessa alleler på bestämda platser (locus). Eftersom kromosomerna existerar i par har vi på samma plats i kromosomparet två möjliga alleler, en nedärvd från mamman och en nedärvd från pappan. Dessa två kan antingen vara samma eller olika alleler, och då kallas individen för homozygot respektive heterozygot beroende på om generna i paret är samma, homo, eller olika, hetero. De flesta genetiska sjukdomar orsakas av recessiva alleler. Ibland kan sjukdomar orsakas av dominanta alleler. Un al·lel (del grec. allḗlōn 'recíproc') és cadascuna de les formes alternatives que pot presentar un gen que ocupa el mateix lloc en un cromosoma determinat o en dos cromosomes homòlegs, i que expressa diferentment un mateix caràcter. Allel – jedna z wersji genu. Allel najczęściej występuje w określonym locus na danym chromosomie homologicznym, jednak pojęcie to odnosi się także do genomu cytoplazmatycznego oraz prokariotycznego. Allele tego samego genu różnią się jednym lub kilkoma nukleotydami. Istnienie więcej niż jednej wersji danego genu określa się jako polimorfizm. Dzięki zdegenerowaniu kodu genetycznego tylko część tych różnic przekłada się na różnice w budowie kodowanych białek. Powoduje to zróżnicowanie właściwości cząsteczek białka kodowanego przez różne allele tego samego genu. 等位基因(allele)旧称對偶基因,是同源染色體内同一个基因座上的多种表现形式;其在细胞有絲分裂时的兩個染色體上的基因座是對應排列的,故细胞遺傳學裡稱其為等位。 在一個二倍體(每條染色體都有兩套)生物體裡,某個基因的基因型是由該基因座的等位基因所決定。在人的一對同源染色體内,等位基因分别來自父辈和母辈的遺傳,其基因型决定了生物的表現型。生物的表現型由一对等位基因的其中一个决定的,稱為顯性基因;而由两个决定的,则称为隐性基因。例如等位基因的一个突變,可产生癌基因,而兩个的突變或丢失,則可導致腫瘤抑制基因,或抑癌基因的突變。這些基因的改變是腫瘤發生的分子基礎。 Un allele (dal Greco ἄλλος állos, "altro") è una delle diverse forme in cui può presentarsi un gene. L'insieme di tutti gli alleli per un particolare carattere costituisce la totalità delle informazioni genetiche che definiscono un gene. Un allele è una variazione della sequenza di nucleotidi che codifica la sintesi di un prodotto genico nello stesso punto (locus genico) su una lunga molecola di DNA. Due alleli possono differire per una sola coppia di basi oppure per diverse migliaia. La maggior parte degli alleli osservati determinano un cambiamento minimo o nullo nella funzione del prodotto genico per il quale codificano. Tuttavia, a volte, alleli diversi possono risultare in tratti fenotipici osservabili diversi, come ad esempio una diversa pigmentazione. Un notevole esempio di ciò è la scoperta da parte di Gregor Mendel che i colori dei fiori, bianchi o viola, nelle piante di pisello dipendono dall'espressione di un unico gene che presenta due alleli: uno determina il colore bianco l'altro quello viola. An allele (UK: /ˈæliːl/, /əˈliːl/; US: /əˈliːl/; modern formation from Greek ἄλλος állos, "other") is a variation of the same sequence of nucleotides at the same place on a long DNA molecule, as described in leading textbooks on genetics and evolution. "The chromosomal or genomic location of a gene or any other genetic element is called a locus (plural: loci) and alternative DNA sequences at a locus are called alleles." The simplest alleles are single nucleotide polymorphisms (SNP). but they can also be insertions and deletions of up to several thousand base pairs. Popular definitions of 'allele' typically refer only to different alleles within genes. For example, the ABO blood grouping is controlled by the ABO gene, which has six common alleles (variants). In population genetics, nearly every living human's phenotype for the ABO gene is some combination of just these six alleles. Most alleles observed result in little or no change in the function of the gene product it codes for. However, sometimes, different alleles can result in different observable phenotypic traits, such as different pigmentation. A notable example of this is Gregor Mendel's discovery that the white and purple flower colors in pea plants were the result of a single gene with two alleles. Nearly all multicellular organisms have two sets of chromosomes at some point in their biological life cycle; that is, they are diploid. In this case, the chromosomes can be paired. Each chromosome in the pair contains the same genes in the same order, and place, along the length of the chromosome. For a given gene, if the two chromosomes contain the same allele, they, and the organism, are homozygous with respect to that gene. If the alleles are different, they, and the organism, are heterozygous with respect to that gene. Is éard atá in ailléil ceann de dhá chineál nó os a chionn de ghéin nó de lócas géiniteach (ar grúpa géinte é go minic). Uaireanta is iad na hailléilí is ciontach le tréithe feinitíopacha ar nós líocha. Achoimre ar "allamorf" atá ann, focal a úsáideadh tráth i gcúrsaí géineolaíochta chun cuntas a thabhairt ar shaghsanna difriúla de ghéin a aithníodh mar fheinitíopaí difriúla. Tagann sé ón ngas Ghréigise ἄλλος (allos) agus alius (eile) na Laidine, focail a thugann αλληλους (allelos) - "a chéile". Tá dhá chuid crómasóm ag an gcuid is mó d'orgánaigh ilcheallacha, rud a fhágann go bhfuil siad . Tugtar crómasóim orthu. Tá aon chóip amháin de gach géin (aon ailléil amháin, mar sin) ar gach crómasóm ag orgánaigh dhioplóideacha. Más ionann iad an dá ailléil, is iad. Má tá siad difriúil le chéile, is iad. De ghnáth gheofá a lán ailléilí ag gach lócas i measc aonán difriúil i speiceas áirithe. Meastar ilchineálacht na n-ailléilí ag lócas mar uimhir na n-ailléilí atá ann nó mar an méid heitrisiogót i bpobal. Ag lócas géineach na n-antaiginí carbaihiotráiteacha sa tíopa fola ABO, aithníonn an ghéineolaíocht chlasaiceach trí ailléil, IA, IB, and IO, a shocraíonn comhoiriúnacht na bhfuilaistrithe. Is féidir le duine aon cheann de shé ghéinitíopa (AA, AO, BB, BO, AB, and OO) a bheith aige, agus iad in ann aon cheann de cheithre fheinitíopa a shíolrú: "A" (a thagann as géinitíopaí homaisiogótacha AA agus as géinitíopaí heitrisigeacha AO), "B" (a thagann as géinitíopaí homaisigeacha BB agus as géinitíopaí heitrisiogótacha BO), heitrisiogóit "AB" agus homaisiogóit "O". Is fios anois gur rang ailleílí ilchineálacha a bhfuil seichimh dhifriúla ADN acu na hailléilí A, O agus O agus iad ag síolrú próitéiní a bhfuil na tréithe céanna acu: tá eolas ar bhreis is 70 ailléil ag an lócas ABO. Is féidir le duine a bhfuil fuil "Tíopa A" aige a bheith ina heitrisiogót AO, ina homaisiogót AA nó ina heitrisiogót A'A le dhá ailléil dhifriúla 'A'. Os alelos são as formas alternativas, gerados por mutações, de um mesmo gene. Estes, por sua vez, estão em posições específicas na extensão de um cromossomo ou locus gênico. Algumas vezes, alelos diferentes podem resultar em uma diferente característica fenotípica, como a pigmentação. Porém, a maioria das variações genéticas resultam em pouca ou nenhuma variação observável. Алельні гени, алелі (від лат. allelos — протилежний) — парні гени, що займають одні й ті самі локуси гомологічних хромосом і визначають альтернативні взаємовиключні стани тієї самої ознаки. Трапляються в межах однієї популяції організмів та визначають різні фенотипи цих організмів.
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dbo:wikiPageWikiLink
dbr:Allele
Subject Item
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dbo:wikiPageWikiLink
dbr:Allele
Subject Item
dbr:Macrostomia
dbo:wikiPageWikiLink
dbr:Allele
Subject Item
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dbo:wikiPageWikiLink
dbr:Allele
Subject Item
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dbo:wikiPageWikiLink
dbr:Allele
Subject Item
dbr:Tumor_suppressor_gene
dbo:wikiPageWikiLink
dbr:Allele
Subject Item
dbr:Marker-assisted_selection
dbo:wikiPageWikiLink
dbr:Allele
Subject Item
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dbo:wikiPageWikiLink
dbr:Allele
Subject Item
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dbo:wikiPageWikiLink
dbr:Allele
Subject Item
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dbo:wikiPageWikiLink
dbr:Allele
Subject Item
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dbo:wikiPageWikiLink
dbr:Allele
Subject Item
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Subject Item
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dbr:Allele
Subject Item
dbr:Mauritius_kestrel
dbo:wikiPageWikiLink
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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dbr:Allele
Subject Item
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dbo:wikiPageWikiLink
dbr:Allele
Subject Item
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dbo:wikiPageWikiLink
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Subject Item
dbr:Actin
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dbr:Allele
Subject Item
dbr:Adams–Oliver_syndrome
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dbr:Allele
Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
dbr:Timothy_Ray_Brown
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dbr:Allele
Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
dbr:William_Bateson
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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dbr:GABRB3
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Subject Item
dbr:GNAS-AS1
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
dbr:Rs6311
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Subject Item
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Subject Item
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Subject Item
dbr:Ras-GRF1
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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dbr:Allele
Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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dbr:Allele
Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
dbr:Dobermann
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dbr:Allele
Subject Item
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dbr:Allele
Subject Item
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dbr:Allele
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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Subject Item
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wikipedia-en:Allele
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