Effects of chronic prenatal ethanol exposure on locomotor activity, and hippocampal weight, neurons, and nitric oxide synthase activity of the young postnatal guinea …
MAS Gibson, NS Butters, JN Reynolds… - Neurotoxicology and …, 2000 - Elsevier
Decreased nitric oxide synthase (NOS)–catalyzed formation of NO from l-arginine may be
involved in ethanol teratogenesis involving the hippocampus. This hypothesis was tested by
determining the effects of chronic prenatal ethanol exposure on locomotor activity and on
hippocampal weight, number of CA1 and CA3 pyramidal cells and dentate gyrus granule
cells, and NOS activity of the postnatal guinea pig. Timed, pregnant guinea pigs received
one of the following chronic oral regimens throughout gestation: 4 g ethanol/kg maternal …
involved in ethanol teratogenesis involving the hippocampus. This hypothesis was tested by
determining the effects of chronic prenatal ethanol exposure on locomotor activity and on
hippocampal weight, number of CA1 and CA3 pyramidal cells and dentate gyrus granule
cells, and NOS activity of the postnatal guinea pig. Timed, pregnant guinea pigs received
one of the following chronic oral regimens throughout gestation: 4 g ethanol/kg maternal …