 | | DRUG: Alimemazine | |
| Entry |
|
|---|
| Name |
Alimemazine (INN);
Trimeprazine (BAN);
Repeltin (TN) |
|---|
| Formula |
C18H22N2S
|
|---|
| Exact mass |
298.1504
|
|---|
| Mol weight |
298.45
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
|
|---|
| Remark |
| Product (DG01101): | D02245<JP> |
|
|---|
| Efficacy |
Antiallergic, H1 receptor antagonist |
|---|
| Comment |
Phenothiazine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04750 | Inflammatory mediator regulation of TRP channels |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07029 | Antipsychotics - phenothiazines |
| map07212 | Histamine H1 receptor antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AD Phenothiazine derivatives
R06AD01 Alimemazine
D07125 Alimemazine (INN)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Alimemazine
D07125 Alimemazine (INN)
Third-class OTC drugs
Inorganic and organic chemicals
Alimemazine
D07125 Alimemazine (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01101 Alimemazine
D07125 Alimemazine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D07125 Alimemazine (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01101 Alimemazine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 21
1 C8y C 25.6200 -20.5800
2 N1y N 26.8800 -19.8800
3 C8y C 25.6200 -21.9100
4 C8x C 24.4300 -19.8800
5 C8y C 28.0700 -20.5800
6 C1b C 26.8800 -18.4100
7 S2x S 26.8800 -22.6800
8 C8x C 24.4300 -22.6100
9 C8x C 23.2400 -20.5800
10 C8y C 28.0700 -21.9800
11 C8x C 29.2600 -19.8800
12 C1c C 28.0700 -17.7100
13 C8x C 23.2400 -21.9100
14 C8x C 29.2600 -22.6800
15 C8x C 30.5200 -20.5800
16 C1b C 28.0700 -16.3100
17 C1a C 29.2600 -18.4800
18 C8x C 30.5200 -21.9100
19 N1c N 29.2600 -15.6100
20 C1a C 30.5200 -16.3800
21 C1a C 29.2600 -14.2100
BOND 23
1 12 16 1
2 12 17 1
3 14 18 2
4 16 19 1
5 19 20 1
6 19 21 1
7 7 10 1
8 9 13 1
9 15 18 1
10 1 2 1
11 1 3 2
12 1 4 1
13 2 5 1
14 2 6 1
15 3 7 1
16 3 8 1
17 4 9 2
18 5 10 2
19 5 11 1
20 6 12 1
21 8 13 2
22 10 14 1
23 11 15 2
|
|---|
|
» Japanese version » Back
|
|
DBGET integrated database retrieval system