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Proopiomelanocortin
Protein
Pro-opiomelanocortin is a precursor polypeptide with 241 amino acid residues. POMC is synthesized in corticotrophs of the anterior pituitary from the 267-amino-acid-long polypeptide precursor pre-pro-opiomelanocortin, by the removal of a... Wikipedia
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Proopiomelanocortin refers to a gene that is expressed in certain cells of the pituitary gland and serves as a precursor for the production of melanocortins ...
Feb 1, 2014 · The POMC gene provides instructions for making a protein called proopiomelanocortin (POMC), which is cut (cleaved) into smaller pieces ...
Nov 27, 2024 · Mutation in POMC gene is associated with severe obesity, hypothyroidism, adrenal insufficiency and abnormal reddish hair pigmentation. In both ...
The skin is a known target organ for the proopiomelanocortin (POMC)-derived neuropeptides alpha-melanocyte stimulating hormone (alpha-MSH), beta-endorphin, ...
Sep 1, 2007 · The CNS POMC system has other functions, including regulation of sexual behaviour, lactation, the reproductive cycle and possibly central ...
Jul 21, 2016 · Patients with rare defects in the gene encoding proopiomelanocortin (POMC) have extreme early-onset obesity, hyperphagia, hypopigmentation, ...