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Oriented cell growth on self-assembled bacteriophage M13 thin films

Chem Commun (Camb). 2008 Nov 7:(41):5185-7. doi: 10.1039/b811039e. Epub 2008 Sep 11.

Abstract

Fibrillar M13 bacteriophages were used as basic building blocks to generate thin films with aligned nanogrooves, which, upon chemical grafting with RGD peptides, guide cell alignment and orient the cell outgrowth along defined directions.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • 3T3 Cells
  • Animals
  • Bacteriophage M13 / chemistry*
  • Biofilms*
  • CHO Cells
  • Cell Adhesion / physiology
  • Cell Physiological Phenomena
  • Cell Proliferation*
  • Cricetinae
  • Cricetulus
  • Extracellular Matrix
  • Fibroblasts / chemistry
  • Mice
  • Microscopy, Atomic Force
  • Microscopy, Phase-Contrast
  • Oligopeptides / chemistry
  • Pharmaceutical Vehicles
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Substances

  • Oligopeptides
  • Pharmaceutical Vehicles
  • arginyl-glycyl-aspartic acid