Abstract
The formation of amyloid fibrils from non-disease-related proteins demonstrates that any protein can adopt this "rogue" form; we show that it is possible to use protic ionic liquids to fibrilize hen egg white lysozyme, and then subsequently to dissolve the fibrils with up to 72% restoration of enzymatic activity.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Amyloid / chemistry*
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Amyloid / metabolism
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Amyloid / ultrastructure
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Animals
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Chickens
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Circular Dichroism
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Ionic Liquids / chemistry*
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Muramidase / chemistry*
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Muramidase / metabolism
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Muramidase / ultrastructure
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Protein Renaturation
Substances
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Amyloid
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Ionic Liquids
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hen egg lysozyme
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Muramidase