Abstract
A biocompatible step-index optical fiber made of poly(ethylene glycol) and alginate hydrogels is demonstrated. The fabricated fiber exhibits excellent light-guiding efficiency in biological tissues. Moreover, the core of hydrogel fibers can be easily doped with functional molecules and nanoparticles for localized light emission, sensing, and therapy.
Keywords:
biocompatible; hydrogels; implantable; optical fibers; sensing.
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Publication types
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Evaluation Study
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Alginates / chemistry
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Animals
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Biocompatible Materials* / chemical synthesis
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Biocompatible Materials* / chemistry
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Colon
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Feasibility Studies
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Glucuronic Acid / chemistry
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Hexuronic Acids / chemistry
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Hydrogels* / chemical synthesis
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Hydrogels* / chemistry
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Lasers
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Materials Testing
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Mechanical Phenomena
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Mice, Inbred BALB C
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Mice, Nude
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Optical Fibers*
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Optical Imaging / instrumentation
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Oximetry / instrumentation
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Oximetry / methods
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Oxygen / blood
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Polyethylene Glycols / chemistry
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Prostheses and Implants
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Spectrum Analysis / instrumentation
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Spectrum Analysis / methods
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Swine
Substances
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Alginates
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Biocompatible Materials
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Hexuronic Acids
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Hydrogels
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Polyethylene Glycols
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Glucuronic Acid
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Oxygen