Abstract
The ability of fibronectin to bind cells can be accounted for by the tetrapeptide L-arginyl-glycyl-L-aspartyl-L-serine, a sequence which is part of the cell attachment domain of fibronectin and present in at least five other proteins. This tetrapeptide may constitute a cellular recognition determinant common to several proteins.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Amino Acid Sequence
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Animals
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Cell Line
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Fibronectins / metabolism*
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Kidney
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Kinetics
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Oligopeptides / metabolism*
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Oligopeptides / pharmacology
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Protein Conformation
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Rats
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Receptors, Cell Surface / drug effects
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Receptors, Cell Surface / metabolism*
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Receptors, Fibronectin
Substances
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Fibronectins
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Oligopeptides
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Receptors, Cell Surface
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Receptors, Fibronectin