CV
Employment
The Sainsbury Wellcome Centre for Neural Circuits and Behaviour and Gatsby Computational Neuroscience Unit, University College London, U.K.
- Head Research Engineer, 2022-
- Head of Neuroinformatics Unit, 2022-
Centre for Advanced Research Computing, University College London, U.K.
Institute of Cancer Research, London, U.K.
- Scientific Software Lead, 2021-2022
- Honorary appointment, 2018-2021
- Advanced Image Analyst and Microscopist, 2017-2018
The Sainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, U.K.
- Research Fellow, 2018-2021
Education
- PhD Neuroscience, King’s College London, 2019
- MRes Biomedical and Translational Science, King’s College London, 2014
- MSci Natural Science, University College London, 2013
Publications
De Vries, M., Dent, L. G., Curry, N., Rowe-Browen, L., Bousgouni, V., Fourkioti, O., Naidoo, R., Sparks, H., Tyson, A., Dunsby, C., Bakal, C. (2025). "Geometric deep learning and multiple-instance learning for 3D cell-shape profiling" Cell Systems v16(3) 101229
Sirmpilatze, N.*, Felder, A.*, Abdulazhanova, D.*, Schwigon, L., Haase, K., Musielak, I., Margrie, T. W., Mouritsen, H., Heyers, D.**, Tyson, A. L.**, Weiler, S.** (2025). "Mapping the magnetoreceptive brain: A 3D digital atlas of the migratory bird Eurasian blackcap (Sylvia atricapilla)" bioRxiv
Domine, C. C. J.*, Carrasco-Davis, R.*, Hollingsworth L., Sirmpilatze, N., Tyson, A. L., Jarvis, D., Barry, C.**, Saxe, A. M.**, (2024). "NeuralPlayground: A Standardised Environment for Evaluating Models of Hippocampus and Entorhinal Cortex" bioRxiv
Keshavarzi, S., Bracey, E. F., Faville, R. A., Campagner, D., Tyson, A. L., Lenzi, S. C., Branco, T., Margrie, T. W. (2022). "Multisensory coding of angular head velocity in the retrosplenial cortex" Neuron v110(3), p532
Tyson, A. L.*, Vélez-Fort, M.*, Rousseau, C. V.*, Cossell, L., Tsitoura, C., Lenzi, S. C., Obenhaus, H. A., Claudi, F., Branco, T., Margrie, T. W. (2022). "Accurate determination of marker location within whole-brain microscopy images" Scientific Reports
Tyson, A. L., Margrie, T. W. (2022). "Mesoscale microscopy and image analysis tools for understanding the brain" Progress in Biophysics and Molecular Biology v168 p81
Tyson, A. L.*, Rousseau, C. V.*, Niedworok, C. J.*, Keshavarzi, S., Tsitoura, C., Cossell, L., Strom, M., Margrie, T. W. (2021). "A deep learning algorithm for 3D cell detection in whole mouse brain image datasets" PLoS Comp Bio 17(5): e1009074.
Claudi, F., Tyson, A. L., Petrucco, L., Margrie, T.W., Portugues, R., Branco, T. (2021). "Visualizing anatomically registered data with Brainrender" eLife 2021;10:e65751
Brown, A. P. Y.*, Cossell, L.*, Strom, M., Tyson, A. L., Vélez-Fort, M., Margrie, T.W. (2021). "Analysis of segmentation ontology reveals the similarities and differences in connectivity onto L2/3 neurons in mouse V1" Sci. Rep. v11 #4983.
Claudi, F.*, Petrucco, L.*, Tyson, A. L.*, Branco, T., Margrie, T. W., Portugues, R. (2020) "BrainGlobe Atlas API: a common interface for neuroanatomical atlases" Journal of Open Source Software, 5(54), 2668
Koundouros, N., Karali, E., Tripp, A., Valle, A., Inglese, P., Perry, N. J. S, Magee, D. J., Virmouni, S. A., Elder, G. A., Tyson, A. L., Luisa Doria, M., van Weverwijk, A., Soares, R. F., Isacke, C. M., Nicholson, J. K., Glen, R. C., Takats, Z., Poulogiannis, G. (2020) "Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids" Cell v181 p1
Jackman, M.*, Marcozzi, C.*, Barbiero, M., Pardo, M., Yu, L., Tyson, A. L., Choudray, J., Pines, J. (2020). "Cyclin B1-Cdk1 facilitates MAD1 release from the nuclear pore to ensure a robust spindle checkpoint" J. Cell Biol. v219(6)
Tyson, A. L., Akhtar, A., Andreae, L. C. (2019). "Optimisation and validation of hydrogel-based brain tissue clearing shows uniform expansion across anatomical regions and spatial scales" Sci. Rep. v9 #12084.
Pervolaraki, E.*, Tyson, A. L.*, Pibiri, F., Poulter, S. L., Reichelt, A. C., Rodgers, R. J., Clapcote, S. J., Lever, C., Andreae, L. C.*, Dachtler, J.* (2019). "The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice" Mol. Autism v10 p8.
McGinnity, C. J., Smith, A. B., Yaakub, S. N., Gerbase, S. W., Gammerman, A., Tyson, A. L., Bell, T. K., Elmasri, M., Barker G. J., Richardson, M. P., Pal, D. K. (2017). "Decreased functional connectivity within a language subnetwork in benign epilepsy with centrotemporal spikes" Epilepsia Open v494 p651.
Tyson, A. L., Hilton, S. T., Andreae, L. C. (2015). "Rapid, simple and inexpensive production of custom 3D printed equipment for large-volume fluorescence microscopy" Int. J. Pharma. v494 p651.
Tyson, A. L. (2013). "What do we know about spatial navigation, and what else could model-based fMRI tell us?" Einstein J. Biol. Med. v29 p32.
Teaching