The Corona Virus Disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Corona Viru... more The Corona Virus Disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) has signicantly changed health care delivery to cancer patients. We have reviewed the available literature on COVID-19 to provide comprehensive information about the impact on the delivery of health care in Cancer Care Facility and adaptations in oncological services. We carried out a literature search in English language using online databases PubMed, Up To Date and Embase with keywords: ‘COVID-19’, ‘coronavirus’ and ‘SARS-CoV-2’, ‘cancer’ from January 2020 to 30th June 2020 focusing on cancer care and different strategies to continue surgical services to cancer patients. Here, we have summarized all currently available information regarding the global impact on the delivery of surgical oncological care and adaptations in Cancer Treatment Protocols due to COVID-19 disease.
The Corona Virus Disease-2019 (COVID-19), one of the most devastating pandemics ever, has left th... more The Corona Virus Disease-2019 (COVID-19), one of the most devastating pandemics ever, has left thousands of cancer patients to their fate. The future course of this pandemic is still an enigma, but health care services are expected to resume soon in a phased manner. This might be a long drawn process and we need to have policies in place, to be able to fight both, the SARS-CoV-2 virus and cancer, simultaneously, and emerge triumphant. An extensive literature search for impact of delay in management of various urological malignancies was carried out. Expert opinions were sought wherever there was paucity of evidence, in order to reach a consensus and come up with recommendations for directing uro-oncology services in the times of COVID-19. The panel recommends deferring treatment of patients with renal cell carcinoma by 3 to 6 months, except for those with ongoing hematuria and/or inferior vena cava thrombus, which warrant immediate surgery. Metastatic renal cell cancers should be st...
The Immunoglobulin G4-related disease (IgG4-RD) is a multisystem inflammatory condition. Pancreat... more The Immunoglobulin G4-related disease (IgG4-RD) is a multisystem inflammatory condition. Pancreaticobiliary manifestations often present as mass lesions that mimic malignancies. The diagnosis is confirmed by histopathological examination, that shows lymphoplasmacytic infiltration, storiform fibrosis, obliterative phlebitis, and positive immunohistochemistry for IgG4. We encountered 3 such patients in a tertiary care hospital in India. Two patients presented with obstructive jaundice and the third with pain abdomen. They had resectable lesions involving the pancreatic head, the right hepatic duct, and gallbladder fundus, respectively, on imaging. Tumor markers were not significantly elevated in any of them. All 3 patients underwent radical surgeries, suspecting malignancy. Surgical specimens showed typical features of IgG4-RD on histomorphology. Serum IgG4 level was elevated in first 2 patients but was normal in sclerosing cholecystitis patient. To conclude, IgG4-RD is a malignant mi...
Background Multiple trials have compared reconstruction techniques used following the resection o... more Background Multiple trials have compared reconstruction techniques used following the resection of distal rectal cancers, including straight colorectal anastomosis (SCA), colonic J pouch (CJP), side-to-end anastomosis (SEA), and transverse coloplasty (TCP). The latest meta-analysis on the subject concluded that all the reservoir techniques produce equally good surgical and functional outcomes compared with SCA. Numerous trials have been published in this regard subsequently. Hence, a network analysis (NMA) was performed to rank these techniques. Methods A literature search of MEDLINE, Embase, and the Cochrane Library from their inception until April 2021 was conducted to identify randomized trials. Functional and surgical outcome data were pooled. ORs and standardized mean differences (MDs) were used as pooled effect size measures. A frequentist NMA model was used. Results Thirty-two trials met the eligibility criteria comprising 3072 patients. CJP showed better functional outcomes,...
The Corona Virus Disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Corona Viru... more The Corona Virus Disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) has signicantly changed health care delivery to cancer patients. We have reviewed the available literature on COVID-19 to provide comprehensive information about the impact on the delivery of health care in Cancer Care Facility and adaptations in oncological services. We carried out a literature search in English language using online databases PubMed, Up To Date and Embase with keywords: ‘COVID-19’, ‘coronavirus’ and ‘SARS-CoV-2’, ‘cancer’ from January 2020 to 30th June 2020 focusing on cancer care and different strategies to continue surgical services to cancer patients. Here, we have summarized all currently available information regarding the global impact on the delivery of surgical oncological care and adaptations in Cancer Treatment Protocols due to COVID-19 disease.
The Corona Virus Disease-2019 (COVID-19), one of the most devastating pandemics ever, has left th... more The Corona Virus Disease-2019 (COVID-19), one of the most devastating pandemics ever, has left thousands of cancer patients to their fate. The future course of this pandemic is still an enigma, but health care services are expected to resume soon in a phased manner. This might be a long drawn process and we need to have policies in place, to be able to fight both, the SARS-CoV-2 virus and cancer, simultaneously, and emerge triumphant. An extensive literature search for impact of delay in management of various urological malignancies was carried out. Expert opinions were sought wherever there was paucity of evidence, in order to reach a consensus and come up with recommendations for directing uro-oncology services in the times of COVID-19. The panel recommends deferring treatment of patients with renal cell carcinoma by 3 to 6 months, except for those with ongoing hematuria and/or inferior vena cava thrombus, which warrant immediate surgery. Metastatic renal cell cancers should be st...
The Immunoglobulin G4-related disease (IgG4-RD) is a multisystem inflammatory condition. Pancreat... more The Immunoglobulin G4-related disease (IgG4-RD) is a multisystem inflammatory condition. Pancreaticobiliary manifestations often present as mass lesions that mimic malignancies. The diagnosis is confirmed by histopathological examination, that shows lymphoplasmacytic infiltration, storiform fibrosis, obliterative phlebitis, and positive immunohistochemistry for IgG4. We encountered 3 such patients in a tertiary care hospital in India. Two patients presented with obstructive jaundice and the third with pain abdomen. They had resectable lesions involving the pancreatic head, the right hepatic duct, and gallbladder fundus, respectively, on imaging. Tumor markers were not significantly elevated in any of them. All 3 patients underwent radical surgeries, suspecting malignancy. Surgical specimens showed typical features of IgG4-RD on histomorphology. Serum IgG4 level was elevated in first 2 patients but was normal in sclerosing cholecystitis patient. To conclude, IgG4-RD is a malignant mi...
Background Multiple trials have compared reconstruction techniques used following the resection o... more Background Multiple trials have compared reconstruction techniques used following the resection of distal rectal cancers, including straight colorectal anastomosis (SCA), colonic J pouch (CJP), side-to-end anastomosis (SEA), and transverse coloplasty (TCP). The latest meta-analysis on the subject concluded that all the reservoir techniques produce equally good surgical and functional outcomes compared with SCA. Numerous trials have been published in this regard subsequently. Hence, a network analysis (NMA) was performed to rank these techniques. Methods A literature search of MEDLINE, Embase, and the Cochrane Library from their inception until April 2021 was conducted to identify randomized trials. Functional and surgical outcome data were pooled. ORs and standardized mean differences (MDs) were used as pooled effect size measures. A frequentist NMA model was used. Results Thirty-two trials met the eligibility criteria comprising 3072 patients. CJP showed better functional outcomes,...
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