【働き】 胃の粘膜が弱ると、胃酸の刺激で、胃炎や胃潰瘍（胃粘膜の傷）を起こしやすくなります。 このお薬は、胃の粘膜を丈夫にします。そして、胃酸に対する抵抗力を高め、胃炎や胃潰瘍の治りをよくします。また、鎮痛薬など他の薬による胃の荒れを予防します。 【薬理】 胃を守る粘液を増やしたり、胃粘膜の血流をよくすることで、胃酸に対する防御機能を高めます。傷ついた組織の修復を助ける作用もあります。 胃酸に対する「防御因子増強薬」です。強い作用があるとはいえませんが、副作用はほとんどありません。この部類で、一番よく処方されています。胃炎や胃潰瘍の治療に広く用いられています。鎮痛薬など他の薬による胃の荒れを予防する目的で、いっしょに処方されることも多いです。
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rebamipideに関するnabinnoのブックマーク (2)
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nabinno 2016/11/09
- rebamipide
- mucosta
- medication
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リンク -
レバミピド - Wikipedia
ムコスタ錠100mg レバミピド（Rebamipide）は、プロスタグランジン（PG）の産生を促進させる成分。胃壁を守る粘膜を増加させるため胃潰瘍の薬として使用される。主に胃薬。商品名ムコスタで大塚製薬が発売、後発医薬品も販売されている。 胃潰瘍の治療薬として開発された。一般に胃潰瘍は、通常はバランスが取れている胃酸分泌に関わる調節機能が障害された場合に、胃液が胃の粘膜を消化する（傷つける）ことによって潰瘍ができるが、レバミピドはプロスタグランジンの産生を促進させることで胃壁を守る粘膜を増やし、胃粘膜の血流を促すことで、胃の胃酸に対する防御機能を高め、胃炎や胃潰瘍の治癒を促進する働きがある。すなわち胃酸分泌をコントロールするのではなく、防御機構を回復させることで胃潰瘍を治療する。 レバミピドの開発以前は胃酸分泌に関係する物質としてはアセチルコリン、ヒスタミンなどが考えられていたが、大塚製薬
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