The complexes CrL3Cl3.2H2O (I), CoL3Cl2.3H2O (2), CoL3Br2.H2O (3), NiL3Cl2.3H2O (4) and CuLCl2 (5... more The complexes CrL3Cl3.2H2O (I), CoL3Cl2.3H2O (2), CoL3Br2.H2O (3), NiL3Cl2.3H2O (4) and CuLCl2 (5), where L is (dimethylphosphinyl)methanamine, were synthesized and characterized by infrared and electronic spectra. The X-ray single crystal analysis of 4 (trigonal, space group R3c, a = 11.340(2), c = 63.708(8) Å, V = 7095(2) Å, Z = 12) revealed a structure containing tris-chelated fac[NiL3] cations in which
ABSTRACT In the title compound, cis-ammine(benzohydrazide-N')-dichloroplatinum(II), cis-[... more ABSTRACT In the title compound, cis-ammine(benzohydrazide-N')-dichloroplatinum(II), cis-[PtCl2(C7H8N2O)(NH3)], the benzoylhydrazine ligand is bonded to the Pt atom through its amino group. The Pt-Cl and Pt-N distances are in the ranges 2.293 (5)-2.318 (5) and 2.01 (1)-2.08 (1) Angstrom, respectively. The arrangement of molecules in the monoclinic unit cell approximates P2(1)/c space-group patterns; however, the true space-group symmetry is P2(1). The two crystallographically independent molecules have significantly different conformations about the Pt-N(hydrazine) bond. The structure is held together by a complicated network of N-H...O and N-H...Cl hydrogen bonds.
The complexes [Pt(bah)2X2], [Pt(NH3)(bah)Cl2].0.5H2O, [Pt(mbah)2X2], and [Pt(NH3)(mbah)Cl2] (bah ... more The complexes [Pt(bah)2X2], [Pt(NH3)(bah)Cl2].0.5H2O, [Pt(mbah)2X2], and [Pt(NH3)(mbah)Cl2] (bah = benzoic acid hydrazide, mbah = 3-methoxybenzoic acid hydrazide; X = Cl, Br, I) have been prepared and characterized by elemental analysis, electric conductivity, IR, 1H NMR, and electronic spectra. A cis-square planar structure with hydrazide ligands coordinated via the NH2-groups has been proposed for these complexes. The complexes have shown a growth-inhibitory effect against Friend leukemia cells in culture comparable to that of the antitumor drug cisplatin.
The complexes CrL3Cl3.2H2O (I), CoL3Cl2.3H2O (2), CoL3Br2.H2O (3), NiL3Cl2.3H2O (4) and CuLCl2 (5... more The complexes CrL3Cl3.2H2O (I), CoL3Cl2.3H2O (2), CoL3Br2.H2O (3), NiL3Cl2.3H2O (4) and CuLCl2 (5), where L is (dimethylphosphinyl)methanamine, were synthesized and characterized by infrared and electronic spectra. The X-ray single crystal analysis of 4 (trigonal, space group R3c, a = 11.340(2), c = 63.708(8) Å, V = 7095(2) Å, Z = 12) revealed a structure containing tris-chelated fac[NiL3] cations in which
ABSTRACT In the title compound, cis-ammine(benzohydrazide-N')-dichloroplatinum(II), cis-[... more ABSTRACT In the title compound, cis-ammine(benzohydrazide-N')-dichloroplatinum(II), cis-[PtCl2(C7H8N2O)(NH3)], the benzoylhydrazine ligand is bonded to the Pt atom through its amino group. The Pt-Cl and Pt-N distances are in the ranges 2.293 (5)-2.318 (5) and 2.01 (1)-2.08 (1) Angstrom, respectively. The arrangement of molecules in the monoclinic unit cell approximates P2(1)/c space-group patterns; however, the true space-group symmetry is P2(1). The two crystallographically independent molecules have significantly different conformations about the Pt-N(hydrazine) bond. The structure is held together by a complicated network of N-H...O and N-H...Cl hydrogen bonds.
The complexes [Pt(bah)2X2], [Pt(NH3)(bah)Cl2].0.5H2O, [Pt(mbah)2X2], and [Pt(NH3)(mbah)Cl2] (bah ... more The complexes [Pt(bah)2X2], [Pt(NH3)(bah)Cl2].0.5H2O, [Pt(mbah)2X2], and [Pt(NH3)(mbah)Cl2] (bah = benzoic acid hydrazide, mbah = 3-methoxybenzoic acid hydrazide; X = Cl, Br, I) have been prepared and characterized by elemental analysis, electric conductivity, IR, 1H NMR, and electronic spectra. A cis-square planar structure with hydrazide ligands coordinated via the NH2-groups has been proposed for these complexes. The complexes have shown a growth-inhibitory effect against Friend leukemia cells in culture comparable to that of the antitumor drug cisplatin.
Uploads
Papers by Nicolay Dodoff