The aim of this study was to compare different methods of detection of Helicobacter pylori (H. py... more The aim of this study was to compare different methods of detection of Helicobacter pylori (H. pylori) in the dental plaque of dyspeptic patients. After recording the clinical indices, culture and polymerase chain reaction (PCR) methods were performed on plaque samples, while rapid urease test in addition to these tests was carried on gastric samples from 67 dyspeptic patients who attended for an upper gastrointestinal endoscopy. Forty-seven of 67 patients were H. pylori-positive in gastric biopsy material whereas the microbial dental plaque from 19 patients demonstrated H. pylori positivity detected by PCR. Among the patients, 25.4% harbored H. pylori both in the stomach and in microbial dental plaque. No significant correlations were found among the presence of H. pylori in the stomach, in plaque, and clinical variables (P > 0.05). Although oral hygiene was observed optimal and the mean of pocket depth was not found to be higher, the prevalence of H. pylori was observed to be higher in dental plaque. According to our results, PCR technique gave the highest detection rate both in gastric biopsy and in dental plaque compared to the other methods used.
A natural polysaccharide, chitosan (poly-N-acetyl glucosaminoglycan), which is a nontoxic and bio... more A natural polysaccharide, chitosan (poly-N-acetyl glucosaminoglycan), which is a nontoxic and bioabsorbable polymer, has been shown to have hemostatic and antibacterial effects. An amino acid, taurine, is considered to be beneficial for regulating the inflammation process. The purpose of this study was to investigate the synergistic effects of taurine and chitosan in the experimental defects at the vestibular bone of maxillary canine teeth in six dogs. Chitosan films were prepared as delivery system with or without taurine and placed in the randomly chosen defects. Biopsies were performed on the postoperative seventh day and routine histological procedures were performed for light and electron microscopic evaluations. For each group, 30 different microscopic areas were examined and the numbers of macrophages and neutrophils in these areas were counted. The mean numbers of both macrophages and neutrophils were found statistically different between the chitosan film incorporated with taurine and free chitosan groups (p < 0.0001 p > 0.05). In addition to the increase in cell counts in both groups, the cytological alterations were more obvious in the chitosan film group incorporated with taurine. Accordingly, taurine appears to enhance the acceleration effect of chitosan on wound healing at early periods. This effect could be considered beneficial in tissue repair in destructive diseases like periodontitis.
To compare the clinical and radiographic effectiveness of dental pulp stem cells (DPSCs) seeded o... more To compare the clinical and radiographic effectiveness of dental pulp stem cells (DPSCs) seeded onto L-PRF and L-PRF alone in the extraction socket of mandibular third molars. This study analyzed 13 patients who required surgical removal of impacted bilateral mandibular third molars. The main outcome measures were the probing pocket depth (PPD) and clinical attachment levels (CAL) that were recorded for the adjacent second molars (LM2) at the baseline and 6 months after surgery. The secondary outcomes were radiographic vertical bone loss (VD) and relative bone density (rBD) distal to the LM2. Twenty-six LM2s were evaluated. After 6 months, the L-PRF and L-PRF + DPSC groups showed a significant reduction in PPD (1.65 ± 1.01 mm and 1.54 ± 0.78 mm) and CAL (2.23 ± 1.45 mm and 2.12 ± 0.74 mm), respectively. There was no difference between the groups for any periodontal parameters. No significant differences were found between the groups regarding the VD or rBD at the sixth month. This study found that there was a significant improvement regarding the PPD, CAL, and VD measurements with the application of L-PRF, both alone and with the addition of DPSC, at the extraction socket. DPSC did not significantly contribute to the results compared to L-PRF therapy alone. This study was registered on 23 December 2020 on ClinicalTrials.gov under the number NCT04641533.
Aim The aim of this study is to investigate patients' satisfaction with their own smiles ... more Aim The aim of this study is to investigate patients' satisfaction with their own smiles and to determine the role of some aspects such as alignment of teeth (crowding, diastemas, displacement of teeth), and appearance of gums (recession, overgrowth, gummy smile) or teeth (color, shape, deposits on surfaces) on self-perception of the smile. Material and Methods Satisfaction with the appearance of teeth and gums was assessed on a 100 mm visual analog scale (VAS) bar. Fifty-three participants (41 females, 12 males) judged their smiles with a questionnaire. Results Patients' satisfaction with their own smiles were 57±31 (mean value±standard deviation) on VAS. They were most satisfied with the alignment of their teeth (61±31), and least satisfied with the appearance of their gums (52±31) when smiling. The importance degree of having tooth displacement was 58±37 for their esthetics, while 68±31 for their comfort standard. Gingival recession, gingival overgrowth, and gummy smile were affecting their smile with a value of 69±29, 72±35, and 74±30, respectively. The number of participants aware of having plaque/calculus on teeth surfaces was 77.4% and the impact of the presence of plaque/calculus on their smile was 56±33. Finally, participants rated in favor of health (79±21), rather than esthetics for a perfect smile in general. Conclusion The results of this study indicate that dental and periodontal health is more valuable in the perception of individuals' own smiles, rather than esthetics.
The aim of this study was to compare different methods of detection of Helicobacter pylori (H. py... more The aim of this study was to compare different methods of detection of Helicobacter pylori (H. pylori) in the dental plaque of dyspeptic patients. After recording the clinical indices, culture and polymerase chain reaction (PCR) methods were performed on plaque samples, while rapid urease test in addition to these tests was carried on gastric samples from 67 dyspeptic patients who attended for an upper gastrointestinal endoscopy. Forty-seven of 67 patients were H. pylori-positive in gastric biopsy material whereas the microbial dental plaque from 19 patients demonstrated H. pylori positivity detected by PCR. Among the patients, 25.4% harbored H. pylori both in the stomach and in microbial dental plaque. No significant correlations were found among the presence of H. pylori in the stomach, in plaque, and clinical variables (P > 0.05). Although oral hygiene was observed optimal and the mean of pocket depth was not found to be higher, the prevalence of H. pylori was observed to be higher in dental plaque. According to our results, PCR technique gave the highest detection rate both in gastric biopsy and in dental plaque compared to the other methods used.
A natural polysaccharide, chitosan (poly-N-acetyl glucosaminoglycan), which is a nontoxic and bio... more A natural polysaccharide, chitosan (poly-N-acetyl glucosaminoglycan), which is a nontoxic and bioabsorbable polymer, has been shown to have hemostatic and antibacterial effects. An amino acid, taurine, is considered to be beneficial for regulating the inflammation process. The purpose of this study was to investigate the synergistic effects of taurine and chitosan in the experimental defects at the vestibular bone of maxillary canine teeth in six dogs. Chitosan films were prepared as delivery system with or without taurine and placed in the randomly chosen defects. Biopsies were performed on the postoperative seventh day and routine histological procedures were performed for light and electron microscopic evaluations. For each group, 30 different microscopic areas were examined and the numbers of macrophages and neutrophils in these areas were counted. The mean numbers of both macrophages and neutrophils were found statistically different between the chitosan film incorporated with taurine and free chitosan groups (p < 0.0001 p > 0.05). In addition to the increase in cell counts in both groups, the cytological alterations were more obvious in the chitosan film group incorporated with taurine. Accordingly, taurine appears to enhance the acceleration effect of chitosan on wound healing at early periods. This effect could be considered beneficial in tissue repair in destructive diseases like periodontitis.
To compare the clinical and radiographic effectiveness of dental pulp stem cells (DPSCs) seeded o... more To compare the clinical and radiographic effectiveness of dental pulp stem cells (DPSCs) seeded onto L-PRF and L-PRF alone in the extraction socket of mandibular third molars. This study analyzed 13 patients who required surgical removal of impacted bilateral mandibular third molars. The main outcome measures were the probing pocket depth (PPD) and clinical attachment levels (CAL) that were recorded for the adjacent second molars (LM2) at the baseline and 6 months after surgery. The secondary outcomes were radiographic vertical bone loss (VD) and relative bone density (rBD) distal to the LM2. Twenty-six LM2s were evaluated. After 6 months, the L-PRF and L-PRF + DPSC groups showed a significant reduction in PPD (1.65 ± 1.01 mm and 1.54 ± 0.78 mm) and CAL (2.23 ± 1.45 mm and 2.12 ± 0.74 mm), respectively. There was no difference between the groups for any periodontal parameters. No significant differences were found between the groups regarding the VD or rBD at the sixth month. This study found that there was a significant improvement regarding the PPD, CAL, and VD measurements with the application of L-PRF, both alone and with the addition of DPSC, at the extraction socket. DPSC did not significantly contribute to the results compared to L-PRF therapy alone. This study was registered on 23 December 2020 on ClinicalTrials.gov under the number NCT04641533.
Aim The aim of this study is to investigate patients' satisfaction with their own smiles ... more Aim The aim of this study is to investigate patients' satisfaction with their own smiles and to determine the role of some aspects such as alignment of teeth (crowding, diastemas, displacement of teeth), and appearance of gums (recession, overgrowth, gummy smile) or teeth (color, shape, deposits on surfaces) on self-perception of the smile. Material and Methods Satisfaction with the appearance of teeth and gums was assessed on a 100 mm visual analog scale (VAS) bar. Fifty-three participants (41 females, 12 males) judged their smiles with a questionnaire. Results Patients' satisfaction with their own smiles were 57±31 (mean value±standard deviation) on VAS. They were most satisfied with the alignment of their teeth (61±31), and least satisfied with the appearance of their gums (52±31) when smiling. The importance degree of having tooth displacement was 58±37 for their esthetics, while 68±31 for their comfort standard. Gingival recession, gingival overgrowth, and gummy smile were affecting their smile with a value of 69±29, 72±35, and 74±30, respectively. The number of participants aware of having plaque/calculus on teeth surfaces was 77.4% and the impact of the presence of plaque/calculus on their smile was 56±33. Finally, participants rated in favor of health (79±21), rather than esthetics for a perfect smile in general. Conclusion The results of this study indicate that dental and periodontal health is more valuable in the perception of individuals' own smiles, rather than esthetics.
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Papers by Emine Alaaddinoglu