CAR T cell therapy for pediatric brain cancer warrants further study
This study shows that this therapy can effectively get to the tumor, and the addition of C7R safely augments antitumor activity.
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Glioma
Uncovering drivers of glioma-related epilepsy
A combination of animal model and patient studies reveals new possibilities to control glioma-related seizures and tumor growth.
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POT1 gene mutation predisposes to glioma and affects survival in a sex-specific manner
Researchers found gender differences in murine glioma lacking the gene Pot1, including survival, immune response, telomere length and DNA markers.
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Brain tumors trigger silencing of neuronal activity
Sudden episodes of confusion and seizures often are the first signs of a malignant brain tumor. At Baylor College of Medicine, Dr. Jeffrey Noebels, director
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Like a mastermind of its own destiny, glioma sets a stage that favors its own growth
“In some regards, glioma brain tumors exhibit Machiavellian behavior,” said Dr. Benjamin Deneen. Machiavellian, as in scheming and cunning, comes from the Italian philosopher Niccolò
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DNA loops matter for NFIA gene expression in brain tumors
The nuclear factor I-A (NFIA) gene is important for both normal brain development and brain tumor growth. One way to discover paths that can lead
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Largest study of malignant brain tumors finds new genetic markers for two distinct glioma subtypes
In 2017, approximately 24,000 people will be diagnosed with malignant brain tumors and 17,000 will die from the disease in the United States. The most
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