The Human Heredity and Health in Africa (H3Africa) Initiative aims to facilitate a contemporary research approach to the study of genomics and environmental determinants of common diseases with the goal of improving the health of African populations. Data and biospecimens from H3Africa projects are available for further use, with access controlled by a Data and Biospecimen Access Committee. The data is housed in the European Genome-phenome Archive and the biospecimens in three H3Africa biorepositories.
This catalogue enables users to search for datasets or biospecimens of interest. Users can browse the catalogue using the simple search.
This catalogue is updated periodically with metadata from studies uploaded from the H3Africa Archive and the corresponding biospecimen metadata uploaded from the following biorepositories:
IBRH3AU: Makerere University, Uganda
IHVN: Institute of Human Virology, Nigeria
CLS: University of the Witswatersrand School of Pathology, South Africa
Some H3Africa publications consist of multiple datasets. The datasets are sometimes submitted seperately to EGA. Use the publications list to view datasets grouped by publications.
Highlights:
High-depth African genomes inform human migration and health. Choudhury et al - (2020)
Title | Acronym | Design | Study Accession | Data use codes | Participants | Biospecimens | Paired |
---|---|---|---|---|---|---|---|
African Collaborative Center for Microbiome and Genomics Research | ACCME | Prospective Longitudinal Cohort | EGAS00001006386 |
DUO:0000014 DUO:0000042 DUO:0000027 DUO:0000024 DUO:0000019 DUO:0000021 |
- | - | - |
Genomic Characterization and Surveillance of Microbial Threats in West Africa | ACEGID | Genome-Wide | EGAS00001007250 |
DUO:0000014 DUO:0000042 DUO:0000027 DUO:0000024 DUO:0000019 DUO_0000021 |
4012 | - | - |
Genomic and Environmental Risk Factors for Cardiometabolic Disease in Africans | AWI-Gen | Gut Microbiome, Control, Case-Control, Cross-Sectional | EGAS00001002482 |
DUO:0000006 DUO:0000027 DUO:0000024 DUO:0000019 |
1548 | 11465 | - |
Immunoglobulin gene diversity in an African population and impact on antibody function in HIV infection | AbGen | see study details |
DUO:0000014 DUO:0000042 DUO:0000027 DUO:0000024 DUO:0000019 |
- | - | - | |
Collaborative African Genomics Network | CAfGEN | Case-Control | EGAS00001002656 |
DUO:0000014 DUO:0000042 DUO:0000027 DUO:0000024 DUO:0000019 |
315 | 1114 | 307 |
Deciphering Developmental Disorders in Africa (DDD-Africa) – Evaluating Clinical Exome Sequencing in an African Setting | DDD-Africa | see study details |
DUO:0000014 DUO:0000042 DUO:0000021 DUO:0000018 DUO:0000027 DUO:0000024 DUO:0000019 |
- | - | - | |
Trauma and Neurobiology: Maternal stress and transgenerational impact. Search for Epigenetic Markers | EPIGEN | Case-Control | EGAS00001006645 |
DUO:0000006 DUO:0000018 DUO:0000027 DUO:0000024 DUO:0000019 |
59 | - | - |
H3Africa consortium WGS | H3ACWGS | Control | EGAS00001005972 |
DUO:0000006 DUO:0000027 DUO:0000024 DUO:0000019 |
410 | 100 | - |
H3Africa Chip Design Study | H3AChip | Control | EGAS00001002976 |
DUO:0000006 DUO:0000027 DUO:0000024 DUO:0000019 |
348 | 151 | 116 |
Hearing Impairment Genetic Studies in Africa | HIGeneS | see study details |
DUO:0000014 DUO:0000042 DUO:0000018 DUO:0000027 DUO:0000024 DUO:0000019 |
- | - | - | |
H3Africa Kidney Disease Research Network | KDRN | Case-Control | EGAS00001006558 |
DUO:0000014 DUO:0000042 DUO:0000027 DUO:0000024 DUO:0000019 DUO:0000026 |
6431 | - | - |
Lassa mammarenavirus | LASV | Cohort | see study details |
DUO:0000014 DUO:0000042 DUO:0000027 DUO:0000024 DUO:0000019 |
- | - | - |
Clinical and genetic studies of hereditary neurological disorders in Mali, West Africa | NEEDI | Cohort | EGAS00001003016 |
DUO:0000014 DUO:0000042 DUO:0000027 DUO:0000024 DUO:0000019 DUO:0000021 |
54 | 627 | 54 |
Genetic variability and antiTB treatment | RAFAgene | None |
NA |
- | - | - | |
Center for Research on the Respiratory Microbiota of African Children (ReMAC) | ReMAC | Longitudinal, cohort study | EGAS00001004401 |
DUO:0000014 DUO:0000042 DUO:0000027 DUO:0000024 DUO:0000019 |
23 | - | - |
The Genomics of Schizophrenia in the South African Xhosa People | SAX | see study details |
DUO:0000007 HP:0000708 DUO:0000018 DUO:0000027 DUO:0000024 DUO:0000019 |
- | 2238 | - | |
Stroke Investigative Research & Educational Network | SIREN | Case-Control | EGAS00001007331 |
DUO:0000007 DUO:0000027 DUO:0000024 DUO:0000019 |
3421 | 5972 | - |
Genetic determinants of susceptibility to trypanosomiasis | TrypanoGEN | Case | EGAS00001002602 |
DUO:0000006 DUO:0000027 DUO:0000024 DUO:0000019 |
233 | - | - |
The genetic determinants of two neglected tropical diseases (Human African Trypanosomiasis (HAT) and Schistosomiasis) | TrypanoGEN+ | Case-Control | EGAS00001007173 |
DUO:0000006 DUO:0000027 DUO:0000024 DUO:0000019 |
183 | - | - |