Giacomo Cavalli
Giacomo Cavalli discovered transgenerational inheritance of chromatin states in metazoan by working on Polycomb and Trithorax group proteins in Drosophila.
The Cavalli lab has shown that the 3D structure of chromosomes can be epigenetically heritable and that it contributes to genome regulation. Furthermore, they provided the first high-resolution description of the principles of genome folding in metazoans.
Finally, the Cavalli lab showed that PcG proteins regulate cell proliferation and have tumour suppression activity in flies.
Supervisors: PhD advisor, Fritz Thoma, ETH Zürich. and Post doc advisor, Renato Paro, University of Heidelberg, Germany.
The Cavalli lab has shown that the 3D structure of chromosomes can be epigenetically heritable and that it contributes to genome regulation. Furthermore, they provided the first high-resolution description of the principles of genome folding in metazoans.
Finally, the Cavalli lab showed that PcG proteins regulate cell proliferation and have tumour suppression activity in flies.
Supervisors: PhD advisor, Fritz Thoma, ETH Zürich. and Post doc advisor, Renato Paro, University of Heidelberg, Germany.
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