gsDesign: Group Sequential Design
Derives group sequential clinical trial designs and describes
their properties. Particular focus on time-to-event, binary, and
continuous outcomes. Largely based on methods described in
Jennison, Christopher and Turnbull, Bruce W., 2000,
"Group Sequential Methods with Applications to Clinical Trials"
ISBN: 0-8493-0316-8.
| Version: |
3.6.5 |
| Depends: |
R (≥ 3.5.0) |
| Imports: |
dplyr (≥ 1.1.0), ggplot2 (≥ 3.1.1), graphics, gt, magrittr, methods, r2rtf, rlang, stats, tibble, tidyr, tools, xtable |
| Suggests: |
covr, data.table, gridExtra, kableExtra, knitr, mvtnorm, ragg, rmarkdown, scales, testthat, utils |
| Published: |
2024-11-14 |
| DOI: |
10.32614/CRAN.package.gsDesign |
| Author: |
Keaven Anderson [aut, cre],
Merck & Co., Inc., Rahway, NJ, USA and its affiliates [cph] |
| Maintainer: |
Keaven Anderson <keaven_anderson at merck.com> |
| BugReports: |
https://github.com/keaven/gsDesign/issues |
| License: |
GPL (≥ 3) |
| URL: |
https://keaven.github.io/gsDesign/,
https://github.com/keaven/gsDesign |
| NeedsCompilation: |
yes |
| Materials: |
README NEWS |
| In views: |
ExperimentalDesign |
| CRAN checks: |
gsDesign results |
Documentation:
| Reference manual: |
gsDesign.pdf |
| Vignettes: |
Conditional error spending functions (source, R code)
Conditional power and conditional error (source, R code)
A gentle introduction to group sequential design (source, R code)
Graphical testing for group sequential design (source)
A cure model calendar-based design (source, R code)
Spending function overview (source, R code)
Overview of survival endpoint design (source, R code)
Vaccine efficacy trial design (source, R code)
Binomial SPRT (source, R code)
gsDesign package overview (source, R code)
Basic time-to-event group sequential design using gsSurv (source, R code)
Multiplicity graphs (source)
Two-sample normal sample size (source, R code)
Integer sample size and event counts (source, R code)
|
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