About: E-55888

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

E-55888 is a drug developed by Esteve, which acts as a potent and selective full agonist at the 5HT7 serotonin receptor, and is used for investigating the role of 5-HT7 receptors in the perception of pain. When administered by itself, E-55888 is anti-hyperalgesic but not analgesic, but when administered alongside morphine, E-55888 was found to significantly increase the analgesic effects.

Property	Value
dbo:abstract	E-55888 es un fármaco desarrollado por los Laboratorios Esteve, que actúa como un agonista completo potente y selectivo del receptor de serotonina 5HT7, y se utiliza para investigar el papel de los receptores 5-HT7 en la percepción del dolor. Cuando se administra solo, E-55888 es antihiperalgésico pero no analgésico, pero cuando se administra junto con morfina, se descubrió que E-55888 aumenta significativamente los efectos analgésicos. (es) E-55888 is a drug developed by Esteve, which acts as a potent and selective full agonist at the 5HT7 serotonin receptor, and is used for investigating the role of 5-HT7 receptors in the perception of pain. When administered by itself, E-55888 is anti-hyperalgesic but not analgesic, but when administered alongside morphine, E-55888 was found to significantly increase the analgesic effects. (en)
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dbp:iupacName	N,N-dimethyl-3-phenethylamine (en)
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dbp:smiles	Cn1ncc-ccccc2CCNC (en)
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rdfs:comment	E-55888 es un fármaco desarrollado por los Laboratorios Esteve, que actúa como un agonista completo potente y selectivo del receptor de serotonina 5HT7, y se utiliza para investigar el papel de los receptores 5-HT7 en la percepción del dolor. Cuando se administra solo, E-55888 es antihiperalgésico pero no analgésico, pero cuando se administra junto con morfina, se descubrió que E-55888 aumenta significativamente los efectos analgésicos. (es) E-55888 is a drug developed by Esteve, which acts as a potent and selective full agonist at the 5HT7 serotonin receptor, and is used for investigating the role of 5-HT7 receptors in the perception of pain. When administered by itself, E-55888 is anti-hyperalgesic but not analgesic, but when administered alongside morphine, E-55888 was found to significantly increase the analgesic effects. (en)
rdfs:label	E-55888 (es) E-55888 (en)
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