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- research-articleJune 2024
Opportunities for incorporating intersectionality into biomedical informatics
- Oliver J. Bear Don't Walk,
- Amandalynne Paullada,
- Avery Everhart,
- Reggie Casanova-Perez,
- Trevor Cohen,
- Tiffany Veinot
Journal of Biomedical Informatics (JOBI), Volume 154, Issue Chttps://doi.org/10.1016/j.jbi.2024.104653Graphical abstractDisplay Omitted
AbstractMany approaches in biomedical informatics (BMI) rely on the ability to define, gather, and manipulate biomedical data to support health through a cyclical research-practice lifecycle. Researchers within this field are often fortunate to work ...
- research-articleFebruary 2024
Useful blunders: Can automated speech recognition errors improve downstream dementia classification?
Journal of Biomedical Informatics (JOBI), Volume 150, Issue Chttps://doi.org/10.1016/j.jbi.2024.104598Abstract Objectives:We aimed to investigate how errors from automatic speech recognition (ASR) systems affect dementia classification accuracy, specifically in the “Cookie Theft” picture description task. We aimed to assess whether imperfect ASR-...
Graphical abstractDisplay Omitted
Highlights- Post-editing methods can enhance Automatic speech recognition (ASR) performance.
- ASR errors can provide important information for downstream dementia classification.
- Our error analysis provides new insights into linguistic ...
- research-articleJanuary 2024
Investigating Generalizability of Speech-based Suicidal Ideation Detection Using Mobile Phones
- Arvind Pillai,
- Subigya Kumar Nepal,
- Weichen Wang,
- Matthew Nemesure,
- Michael Heinz,
- George Price,
- Damien Lekkas,
- Amanda C. Collins,
- Tess Griffin,
- Benjamin Buck,
- Sarah Masud Preum,
- Trevor Cohen,
- Nicholas C. Jacobson,
- Dror Ben-Zeev,
- Andrew Campbell
Proceedings of the ACM on Interactive, Mobile, Wearable and Ubiquitous Technologies (IMWUT), Volume 7, Issue 4Article No.: 174, Pages 1–38https://doi.org/10.1145/3631452Speech-based diaries from mobile phones can capture paralinguistic patterns that help detect mental illness symptoms such as suicidal ideation. However, previous studies have primarily evaluated machine learning models on a single dataset, making their ...
- research-articleJanuary 2024
Retrieval augmentation of large language models for lay language generation
Journal of Biomedical Informatics (JOBI), Volume 149, Issue Chttps://doi.org/10.1016/j.jbi.2023.104580AbstractThe complex linguistic structures and specialized terminology of expert-authored content limit the accessibility of biomedical literature to the general public. Automated methods have the potential to render this literature more interpretable to ...
Graphical abstractDisplay Omitted
Highlights- Problem: Automated lay summary generation can improve the accessibility of health information, but is challenging because of the need to provide background information absent in source documents.
- What is already known: Current models ...
- research-articleSeptember 2023
The Power of Speech in the Wild: Discriminative Power of Daily Voice Diaries in Understanding Auditory Verbal Hallucinations Using Deep Learning
- Weichen Wang,
- Weizhe Xu,
- Ayesha Chander,
- Subigya Nepal,
- Benjamin Buck,
- Serguei Pakhomov,
- Trevor Cohen,
- Dror Ben-Zeev,
- Andrew Campbell
Proceedings of the ACM on Interactive, Mobile, Wearable and Ubiquitous Technologies (IMWUT), Volume 7, Issue 3Article No.: 133, Pages 1–29https://doi.org/10.1145/3610890Mobile phone sensing is increasingly being used in clinical research studies to assess a variety of mental health conditions (e.g., depression, psychosis). However, in-the-wild speech analysis -- beyond conversation detecting -- is a missing component of ...
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- research-articleApril 2023
Discerning conversational context in online health communities for personalized digital behavior change solutions using Pragmatics to Reveal Intent in Social Media (PRISM) framework
Journal of Biomedical Informatics (JOBI), Volume 140, Issue Chttps://doi.org/10.1016/j.jbi.2023.104324Graphical abstractDisplay Omitted
Abstract BackgroundOnline health communities (OHCs) have emerged as prominent platforms for behavior modification, and the digitization of online peer interactions has afforded researchers with unique opportunities to model multilevel mechanisms that ...
- research-articleFebruary 2022
Fully automated detection of formal thought disorder with Time-series Augmented Representations for Detection of Incoherent Speech (TARDIS)
- Weizhe Xu,
- Weichen Wang,
- Jake Portanova,
- Ayesha Chander,
- Andrew Campbell,
- Serguei Pakhomov,
- Dror Ben-Zeev,
- Trevor Cohen
Journal of Biomedical Informatics (JOBI), Volume 126, Issue Chttps://doi.org/10.1016/j.jbi.2022.103998Graphical abstractDisplay Omitted
Highlights- Quantifying coherence in speech identifies formal thought disorder automatically.
Formal thought disorder (ThD) is a clinical sign of schizophrenia amongst other serious mental health conditions. ThD can be recognized by observing incoherent speech - speech in which it is difficult to perceive connections between ...
- articleJanuary 2022
Quantum Mathematics in Artificial Intelligence
Journal of Artificial Intelligence Research (JAIR), Volume 72Pages 1307–1341https://doi.org/10.1613/jair.1.12702In the decade since 2010, successes in artificial intelligence have been at the forefront of computer science and technology, and vector space models have solidified a position at the forefront of artificial intelligence. At the same time, quantum ...
- research-articleJuly 2021
Augmenting aer2vec: Enriching distributed representations of adverse event report data with orthographic and lexical information
Journal of Biomedical Informatics (JOBI), Volume 119, Issue Chttps://doi.org/10.1016/j.jbi.2021.103833Graphical abstractDisplay Omitted
Highlights- Distributed representations (embeddings) are derived from ADE report data.
- ...
Adverse Drug Events (ADEs) are prevalent, costly, and sometimes preventable. Post-marketing drug surveillance aims to monitor ADEs that occur after a drug is released to market. Reports of such ADEs are aggregated by reporting systems, ...
- research-articleMay 2021
Using computable knowledge mined from the literature to elucidate confounders for EHR-based pharmacovigilance
Journal of Biomedical Informatics (JOBI), Volume 117, Issue Chttps://doi.org/10.1016/j.jbi.2021.103719Graphical abstractDisplay Omitted
Highlights- Drug safety research asks causal questions but must rely on observational data.
Drug safety research asks causal questions but relies on observational data. Confounding bias threatens the reliability of studies using such data. The successful control of confounding requires knowledge of ...
- research-articleFebruary 2019
Rapamycin − mTOR + BRAF = ? Using relational similarity to find therapeutically relevant drug-gene relationships in unstructured text
- Safa Fathiamini,
- Amber M. Johnson,
- Jia Zeng,
- Vijaykumar Holla,
- Nora S. Sanchez,
- Funda Meric-Bernstam,
- Elmer V. Bernstam,
- Trevor Cohen
Journal of Biomedical Informatics (JOBI), Volume 90, Issue Chttps://doi.org/10.1016/j.jbi.2019.103094Graphical abstractDisplay Omitted
Highlights- Compare relational and attributional similarity to find drugs that target genes.
- research-articleApril 2017
Embedding of semantic predications
Journal of Biomedical Informatics (JOBI), Volume 68, Issue CPages 150–166https://doi.org/10.1016/j.jbi.2017.03.003Display Omitted We develop a neural-probabilistic approach to represent semantic predications.This is compared to a prior representational approach across a number of tasks.Application areas are pharmacovigilance and drug repurposing.The neural-...
- research-articleJune 2016
Improving the utility of MeSHź terms using the TopicalMeSH representation
Journal of Biomedical Informatics (JOBI), Volume 61, Issue CPages 77–86https://doi.org/10.1016/j.jbi.2016.03.013Display Omitted TopicalMeSH representation combines information from topic models and MeSH terms.TopicalMeSH has better document retrieval performance than MeSH.TopicalMeSH has better classification performance than MeSH and several alternatives. ...
- research-articleDecember 2014
Identifying plausible adverse drug reactions using knowledge extracted from the literature
Journal of Biomedical Informatics (JOBI), Volume 52, Issue CPages 293–310https://doi.org/10.1016/j.jbi.2014.07.011Display Omitted We evaluate PSI-based identification of relationships between drugs and ADRs.PSI can incorporate relations and concepts and infer reasoning pathways.PSI is more predictive than a co-occurrence based model.Reasoning pathways suggest ...
- bookDecember 2013
Cognitive Informatics in Health and Biomedicine: Case Studies on Critical Care, Complexity and Errors
Enormous advances in information technology have permeated essentially all facets of life in the past two decades. Formidable challenges remain in fostering tools that enhance productivity but are sensitive to work practices. Cognitive Informatics (CI) ...
- ArticleJuly 2013
Orthogonality and Orthography: Introducing Measured Distance into Semantic Space
QI 2013: Selected Papers of the 7th International Conference on Quantum Interaction - Volume 8369Pages 34–46https://doi.org/10.1007/978-3-642-54943-4_4This paper explores a new technique for encoding structured information into a semantic model, for the construction of vector representations of words and sentences. As an illustrative application, we use this technique to compose robust representations ...
- ArticleApril 2013
Identifying persuasive qualities of decentralized peer-to-peer online social networks in public health
PERSUASIVE'13: Proceedings of the 8th international conference on Persuasive TechnologyPages 155–160https://doi.org/10.1007/978-3-642-37157-8_19Online social networks as behavior change support systems have been rapidly gaining in popularity. These networks have been studied by public health specialists from the point of view of traditional behavior change theories. However, scant research ...
- articleJanuary 2013
Understanding the nature of information seeking behavior in critical care: Implications for the design of health information technology
Artificial Intelligence in Medicine (AIIM), Volume 57, Issue 1Pages 21–29https://doi.org/10.1016/j.artmed.2012.10.002Objective: Information in critical care environments is distributed across multiple sources, such as paper charts, electronic records, and support personnel. For decision-making tasks, physicians have to seek, gather, filter and organize information ...
- research-articleDecember 2012
Avatar-based simulation in the evaluation of diagnosis and management of mental health disorders in primary care
- Rachel M. Satter,
- Trevor Cohen,
- Pierina Ortiz,
- Kanav Kahol,
- James Mackenzie,
- Carol Olson,
- Mina Johnson,
- Vimla L. Patel
Journal of Biomedical Informatics (JOBI), Volume 45, Issue 6Pages 1137–1150https://doi.org/10.1016/j.jbi.2012.07.009Graphical abstractDisplay Omitted Highlights Innovative tool to access cognitive reasoning and decision-making was developed. Avatar-based assessment tool developed to train physicians to diagnose MDD and PTSD. Assessed diagnostic and management ...
- research-articleDecember 2012
Discovering discovery patterns with predication-based Semantic Indexing
Journal of Biomedical Informatics (JOBI), Volume 45, Issue 6Pages 1049–1065https://doi.org/10.1016/j.jbi.2012.07.003Graphical abstractDisplay Omitted Highlights PSI represents concepts and relations in hyperdimensional space. PSI is used to infer discovery patterns from known therapeutic relationships. These patterns are used to recover therapeutic relationships for ...