Constraint-based mining techniques on sequence databases have been studied extensively the last few years and efficient algorithms enable to compute complete collections of patterns (e.g., sequences) which satisfy conjunctions of monotonic and/or anti-...

We report a comprehensive evaluation of the topological structure of protein-protein interaction (PPI) networks by mining and analyzing graphs constructed from the publicly available popular data sets to the bioinformatics research community. We compare ...

Fanconi Anemia (FA) is a rare autosomal genetic disease with multiple birth defects and severe childhood complications for its patients. The lack of sequence homology of the entire FA Complementation Group proteins in such as FANCC, FANCG, FANCA makes ...

The ubiquity of microarray expression data in state-of-the-art biology has been well established. The widespread adoption of this technology coupled with the significant volume of image-based experimental data generated per experiment (averaging 40 MB), ...

Phylogenetic profiles of proteins - strings of ones and zeros encoding respectively the presence and absence of proteins in a group of genomes - have recently been used to identify homologous proteins and/or proteins that are functionally linked, such ...

In the context of genome research, the method of gene expression analysis has been used for several years. Related microarray experiments are conducted all over the world, and consequently, a vast amount of microarray data sets are produced. Having ...

Advances in bioinformatics are providing the foundations for the convergence of agribusiness, healthcare, pharmaceuticals, computing and other fields, into what promises to be the largest industry in the world, the life sciences industry. Much of the ...