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Interpreting Gene Profiles from Biomedical Literature Mining with Self Organizing Maps

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Advances in Neural Networks - ISNN 2006 (ISNN 2006)

Part of the book series: Lecture Notes in Computer Science ((LNTCS,volume 3973))

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Abstract

We present an approach to interpret gene profiles derived from biomedical literature using Self Organizing Maps (SOMs). Comparison of different clustering algorithms shows that SOMs perform better in grouping high dimensional gene profiles when a lot of noise is present in the data. Qualitative analysis of the clustering results prove that SOMs allow an in-depth interpretation of gene profiles with biological relevance.

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Authors and Affiliations

  1. Department of Electrical Engineering, University of Leuven, B3000, Belgium

    Shi Yu, Steven Van Vooren, Bert Coessens & Bart De Moor

Authors
  1. Shi Yu
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  2. Steven Van Vooren
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  3. Bert Coessens
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  4. Bart De Moor
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Editor information

Editors and Affiliations

  1. Department of Mechanical and Automation Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China

    Jun Wang

  2. Computational Intelligence Laboratory, School of Computer Science and Engineering, University of Electronic Science and Technology of China, 610054, Chengdu, P.R. China

    Zhang Yi

  3. Department of Electrical Engineering, University of Louisville, 40292, Louisville, KY, U.S.A

    Jacek M. Zurada

  4. Laboratory for Computational Biology, Shanghai Center for Systems Biomedicine, 800 Dong Chuan Rd, 200240, Shanghai, China

    Bao-Liang Lu

  5. School of Electrical and Electronic Engineering, University of Manchester, UK

    Hujun Yin

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© 2006 Springer-Verlag Berlin Heidelberg

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Yu, S., Van Vooren, S., Coessens, B., De Moor, B. (2006). Interpreting Gene Profiles from Biomedical Literature Mining with Self Organizing Maps. In: Wang, J., Yi, Z., Zurada, J.M., Lu, BL., Yin, H. (eds) Advances in Neural Networks - ISNN 2006. ISNN 2006. Lecture Notes in Computer Science, vol 3973. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11760191_93

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  • DOI: https://doi.org/10.1007/11760191_93

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-34482-7

  • Online ISBN: 978-3-540-34483-4

  • eBook Packages: Computer ScienceComputer Science (R0)

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