Overview
- A concise, easy-to-follow text, serving as a valuable introduction to contemporary cell biology and offering insight into the key research directions in the field
- Introduces the current big bio-databases, and why and how they can be used to develop and support systems biology research
- Includes supplementary material: sn.pub/extras
Part of the book series: Computational Biology (COBO, volume 13)
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About this book
Today, as hundreds of genomes have been sequenced and thousands of proteins and more than ten thousand metabolites have been identi?ed, navigating safely through this wealth of information without getting completely lost has become crucial for research in, and teaching of, molecular biology. Consequently, a considerable number of tools have been developed and put on the market in the last two decades that describe the multitude of potential/putative interactions between genes, proteins, metabolites, and other biologically relevant compounds in terms of metabolic, genetic, signaling, and other networks, their aim being to support all sorts of explorations through bio-data bases currently called Systems Biology. As a result, navigating safely through this wealth of information-processing tools has become equally crucial for successful work in molecular biology. To help perform such navigation tasks successfully, this book starts by providing an extremely useful overview of existing tools for ?nding (or designing) and inv- tigating metabolic, genetic, signaling, and other network databases, addressing also user-relevant practical questions like • Is the database viewable through a web browser? • Is there a licensing fee? • What is the data type (metabolic, gene regulatory, signaling, etc. )? • Is the database developed/maintained by a curator or a computer? • Is there any software for editing pathways? • Is it possible to simulate the pathway? It then goes on to introduce a speci?c such tool, that is, the fabulous “Cell - lustrator 3. 0” tool developed by the authors.
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Table of contents (6 chapters)
Bibliographic Information
Book Title: Foundations of Systems Biology
Book Subtitle: Using Cell Illustrator and Pathway Databases
Authors: Masao Nagasaki, Ayumu Saito, Atsushi Doi, Hiroshi Matsuno, Satoru Miyano
Series Title: Computational Biology
DOI: https://doi.org/10.1007/978-1-84882-023-4
Publisher: Springer London
eBook Packages: Computer Science, Computer Science (R0)
Copyright Information: Springer-Verlag London 2009
Hardcover ISBN: 978-1-84882-022-7Published: 06 April 2009
Softcover ISBN: 978-1-4471-6872-0Published: 30 April 2017
eBook ISBN: 978-1-84882-023-4Published: 21 April 2009
Series ISSN: 1568-2684
Series E-ISSN: 2662-2432
Edition Number: 1
Number of Pages: XII, 155
Topics: Life Sciences, general, Computational Biology/Bioinformatics, Simulation and Modeling, Cell Biology