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Shape and Facet Analyses of Alveolar Airspaces of the Lung

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Shape in Medical Imaging (ShapeMI 2018)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 11167))

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Abstract

Changes in lung volume during the breathing cycle and also lung diseases are likely to deform even the smallest airspace units, the alveoli. This study reports general ideas to investigate such changes with 3D digital image processing. It comprises morphological characterizations like volume and surface, an evaluation of the angle distribution between facets formed by the septal walls, the number of neighboring alveoli and a shape analysis of the alveolar airspace. The software used is open-source and custom programs are available at:

http://github.com/romangrothausmann/.

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Acknowledgement

Many thanks go to David Legland for his MatImage [19] support and for helping to use it also within octave [5] and to Sheila Fryk for polishing the English language as native speaker.

Author information

Authors and Affiliations

  1. Institute of Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany

    Roman Grothausmann, Christian Mühlfeld, Matthias Ochs & Lars Knudsen

  2. REBIRTH Cluster of Excellence, Hannover, Germany

    Roman Grothausmann, Christian Mühlfeld, Matthias Ochs & Lars Knudsen

  3. Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Hannover, Germany

    Roman Grothausmann, Christian Mühlfeld, Matthias Ochs & Lars Knudsen

Authors
  1. Roman Grothausmann
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  2. Christian Mühlfeld
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  3. Matthias Ochs
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  4. Lars Knudsen
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Corresponding author

Correspondence to Roman Grothausmann .

Editor information

Editors and Affiliations

  1. German Center for Neurodegenerative Diseases, Bonn, Germany

    Martin Reuter

  2. Ludwig Maximilian University of Munich, Munich, Germany

    Christian Wachinger

  3. École de Technologie Supérieure, Montreal, QC, Canada

    Hervé Lombaert

  4. Kitware Inc., Carrboro, NC, USA

    Beatriz Paniagua

  5. University of Basel, Basel, Switzerland

    Marcel Lüthi

  6. Massachusetts Institute of Technology, Cambridge, MA, USA

    Bernhard Egger

1 Electronic supplementary material

Below is the link to the electronic supplementary material.

Supplementary material 1 (mp4 3550 KB)

Supplementary material 2 (pdf 20027 KB)

Appendices

A Catalogue

Fig. 10.
figure 10

Catalog of all analyzed alveoli/cluster

Full size image

Excerpt from the catalog comprising integral measures (such as in Fig. 4) and all individually analyzed alveoli/cluster (such as in Fig. 3). The full catalog can be found as a separate PDF in the supplementary data.

B Video

Fig. 11.
figure 11

Rotating view of alveolus

Full size image

Video of the rotating alveolus shown in Fig. 3, visualizing the shape, the fitted ellipsoid (blue), the detected facets, the opening and its lid (transparent gray).

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Grothausmann, R., Mühlfeld, C., Ochs, M., Knudsen, L. (2018). Shape and Facet Analyses of Alveolar Airspaces of the Lung. In: Reuter, M., Wachinger, C., Lombaert, H., Paniagua, B., Lüthi, M., Egger, B. (eds) Shape in Medical Imaging. ShapeMI 2018. Lecture Notes in Computer Science(), vol 11167. Springer, Cham. https://doi.org/10.1007/978-3-030-04747-4_5

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  • DOI: https://doi.org/10.1007/978-3-030-04747-4_5

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-04746-7

  • Online ISBN: 978-3-030-04747-4

  • eBook Packages: Computer ScienceComputer Science (R0)

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