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U-Net with Graph Based Smoothing Regularizer for Small Vessel Segmentation on Fundus Image

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Neural Information Processing (ICONIP 2019)

Part of the book series: Communications in Computer and Information Science ((CCIS,volume 1143))

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Abstract

The detection of retinal blood vessels, especially the changes of small vessel condition is the most important indicator to identify the vascular network of the human body. Existing techniques focused mainly on shape of the large vessels, which is not appropriate for the disconnected small and isolated vessels. Paying attention to the low contrast small blood vessel in fundus region, first time we proposed to combine graph based smoothing regularizer with the loss function in the U-net framework. The proposed regularizer treated the image as two graphs by calculating the graph laplacians on vessel regions and the background regions on the image. The potential of the proposed graph based smoothing regularizer in reconstructing small vessel is compared over the classical U-net with or without regularizer. Numerical and visual results shows that our developed regularizer proved its effectiveness in segmenting the small vessels and reconnecting the fragmented retinal blood vessels.

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Acknowledgments

This work was partly supported by JSPS KAKENHI Grant Number 16K00239 and 18F18112.

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Correspondence to Lukman Hakim or Takio Kurita .

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Hakim, L., Yudistira, N., Kavitha, M., Kurita, T. (2019). U-Net with Graph Based Smoothing Regularizer for Small Vessel Segmentation on Fundus Image. In: Gedeon, T., Wong, K., Lee, M. (eds) Neural Information Processing. ICONIP 2019. Communications in Computer and Information Science, vol 1143. Springer, Cham. https://doi.org/10.1007/978-3-030-36802-9_55

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  • DOI: https://doi.org/10.1007/978-3-030-36802-9_55

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-36801-2

  • Online ISBN: 978-3-030-36802-9

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