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3D Probabilistic Segmentation and Volumetry from 2D Projection Images

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Thoracic Image Analysis (TIA 2020)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 12502))

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Abstract

X-Ray imaging is quick, cheap and useful for front-line care assessment and intra-operative real-time imaging (e.g., C-Arm Fluoroscopy). However, it suffers from projective information loss and lacks vital volumetric information on which many essential diagnostic biomarkers are based on. In this paper we explore probabilistic methods to reconstruct 3D volumetric images from 2D imaging modalities and measure the models’ performance and confidence. We show our models’ performance on large connected structures and we test for limitations regarding fine structures and image domain sensitivity. We utilize fast end-to-end training of a 2D-3D convolutional networks, evaluate our method on 117 CT scans segmenting 3D structures from digitally reconstructed radiographs (DRRs) with a Dice score of \(0.91 \pm 0.0013\). Source code will be made available by the time of the conference.

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References

  1. Albarqouni, S., Fotouhi, J., Navab, N.: X-ray in-depth decomposition: revealing the latent structures. In: MICCAI (2017)

    Google Scholar 

  2. Aubert, B., Vergari, C., Ilharreborde, B., Courvoisier, A., Skalli, W.: 3D reconstruction of rib cage geometry from biplanar radiographs using a statistical parametric model approach. Comput. Methods Biomech. Biomed. Eng. Imag. Visual. 4(5), 281–295 (2016). https://doi.org/10.1080/21681163.2014.913990

  3. Baumgartner, C.F.,et al.: PHiSeg: capturing uncertainty in medical image segmentation. In: MICCAI, pp. 1–14 (2019)

    Google Scholar 

  4. Budd, S., et al.: Confident head circumference measurement from ultrasound with real-time feedback for sonographers. In: MICCAI (2019)

    Google Scholar 

  5. Çiçek, Ö., Abdulkadir, A., Lienkamp, S.S., Brox, T., Ronneberger, O.: 3d u-net: learning dense volumetric segmentation from sparse annotation. In: Ourselin, S., et al. (eds.) MICCAI (2016)

    Google Scholar 

  6. Dumoulin, V., Visin, F.: A guide to convolution arithmetic for deep learning. arXiv preprint arXiv:1603.07285 (2016)

  7. Gal, Y., Ghahramani, Z.: Dropout as a bayesian approximation: representing model uncertainty in deep learning. In: ICML (2016)

    Google Scholar 

  8. Henzler, P., Rasche, V., Ropinski, T., Ritschel, T.: Single-image tomography: 3d volumes from 2d cranial x-rays. Comput. Graph. Forum 37(2), 377–388 (2018). https://doi.org/10.1111/cgf.13369

  9. Jian, W.: ITK-based implementation of two-projection 2D/3D registration method with an application in patient setup for external beam radiotherapy. In: Insight Journal (2010)

    Google Scholar 

  10. Kainz, B., Voglreiter, P., Sereinigg, M., et al.: High-Resolution Contrast Enhanced Multi-Phase Hepatic Computed Tomography Data from a Porcine Radio-Frequency Ablation Study (2014)

    Google Scholar 

  11. Koehler, C., Wischgoll, T.: Knowledge-assisted reconstruction of the human RIB cage and lungs. IEEE Comput. Graph. Appl. 30(1), 17–29 (2009)

    Article  Google Scholar 

  12. Kroes, T., Post, F.H., Botha, C.P.: Exposure render: An interactive photo-realistic volume rendering framework. PLoS ONE 7(7), 75 (2012)

    Google Scholar 

  13. Lin, C.H., Kong, C., Lucey, S.: Learning efficient point cloud generation for dense 3d object reconstruction. In: Thirty-Second AAAI Conference on Artificial Intelligence (2018)

    Google Scholar 

  14. Rubin, G.D.: Computed tomography: revolutionizing the practice of medicine for 40 years. Radiology 273(2S), S45–S74 (2014). https://doi.org/10.1148/radiol.14141356, pMID: 25340438

  15. Sun, X., et al.: Pix3d: dataset and methods for single-image 3d shape modeling. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 2974–2983 (2018)

    Google Scholar 

  16. Sun, Y., Tzeng, E., Darrell, T., Efros, A.A.: Unsupervised domain adaptation through self-supervision (2019)

    Google Scholar 

  17. Van Dyck, P., Vanhoenacker, F.M., Van den Brande, P., De Schepper, A.M.: Imaging of pulmonary tuberculosis. In: European Radiology (2003)

    Google Scholar 

  18. Wang, X., Peng, Y., Lu, L., Lu, Z., Bagheri, M., Summers, R.M.: ChestX-ray8: Hospital-scale Chest X-ray Database and Benchmarks on Weakly-Supervised Classification and Localization of Common Thorax Diseases (2017)

    Google Scholar 

  19. Yan, X., Yang, J., Yumer, E., Guo, Y., Lee, H.: Perspective transformer nets: learning single-view 3D object reconstruction without 3d supervision. In: NeurIPS (2016)

    Google Scholar 

  20. Ying, X., Guo, H., Ma, K., Wu, J., Weng, Z., Zheng, Y.: X2ct-GAN: Reconstructing CT from biplanar x-rays with generative adversarial networks. In: The IEEE Conference on Computer Vision and Pattern Recognition (CVPR), June 2019

    Google Scholar 

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Acknowledgments

Funding for this work was received by DoC of Imperial College London and the MAVEHA (EP/S013687/1) grant (A.V., D.R., B.K.). S.B. is supported by EP/S022104/1 and B.H. by the London Medical Imaging and AI Centre for Value Based Healthcare (19923). The authors would also like to thank NVIDIA corp for the donation of GPU resources.

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Correspondence to Athanasios Vlontzos .

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Vlontzos, A., Budd, S., Hou, B., Rueckert, D., Kainz, B. (2020). 3D Probabilistic Segmentation and Volumetry from 2D Projection Images. In: Petersen, J., et al. Thoracic Image Analysis. TIA 2020. Lecture Notes in Computer Science(), vol 12502. Springer, Cham. https://doi.org/10.1007/978-3-030-62469-9_5

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  • DOI: https://doi.org/10.1007/978-3-030-62469-9_5

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-62468-2

  • Online ISBN: 978-3-030-62469-9

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