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Selection of Pseudo-Annotated Data for Adverse Drug Reaction Classification Across Drug Groups

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Analysis of Images, Social Networks and Texts (AIST 2021)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 13217))

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Abstract

Automatic monitoring of adverse drug events (ADEs) or reactions (ADRs) is currently receiving significant attention from the biomedical community. In recent years, user-generated data on social media has become a valuable resource for this task. Neural models have achieved impressive performance on automatic text classification for ADR detection. Yet, training and evaluation of these methods are carried out on user-generated texts about a targeted drug. In this paper, we assess the robustness of state-of-the-art neural architectures across different drug groups. We investigate several strategies to use pseudo-labeled data in addition to a manually annotated train set. Out-of-dataset experiments diagnose the bottleneck of supervised models in terms of breakdown performance, while additional pseudo-labeled data improves overall results regardless of the text selection strategy.

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Notes

  1. 1.

    The terms ADEs and adverse drug reactions (ADRs) are often used interchangeably.

  2. 2.

    https://www.fda.gov/about-fda/fda-basics/fact-sheet-fda-glance.

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Acknowledgments

This work was supported by the Russian Science Foundation grant # 18-11-00284.

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Correspondence to Elena Tutubalina .

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Alimova, I., Tutubalina, E. (2022). Selection of Pseudo-Annotated Data for Adverse Drug Reaction Classification Across Drug Groups. In: Burnaev, E., et al. Analysis of Images, Social Networks and Texts. AIST 2021. Lecture Notes in Computer Science, vol 13217. Springer, Cham. https://doi.org/10.1007/978-3-031-16500-9_4

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  • DOI: https://doi.org/10.1007/978-3-031-16500-9_4

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  • Publisher Name: Springer, Cham

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