Location via proxy:   [ UP ]  
[Report a bug]   [Manage cookies]                
Skip to main content

Artificial Neural Networks in the Discrimination of Alzheimer’s Disease

  • Conference paper
ENTERprise Information Systems (CENTERIS 2011)

Part of the book series: Communications in Computer and Information Science ((CCIS,volume 221))

Included in the following conference series:

Abstract

Alzheimer’s disease (AD) is the most common cause of dementia, a general term for memory loss and other intellectual abilities. The Electroencephalogram (EEG) has been used as diagnosis tool for dementia over several decades. The main objective of this work was to develop an Artificial Neural Network (ANN) to classify EEG signals between AD patients and Control subjects. For this purpose two different methodologies and variations were used. The Short time Fourier transform (STFT) was applied to one of the methodologies and the Wavelet Transform (WT) was applied to the other methodology. The studied features of the EEG signals were the Relative Power in conventional EEG bands (delta, theta, alpha, beta and gamma) and their associated Spectral Ratios (r 1, r 2, r 3 and r 4). The best classification was performed by the ANN using the WT Biorthogonal 3.5 with AROC of 0.97, Sensitivity of 92.1%, Specificity of 90.8% and 91.5% of Accuracy.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  1. Ballard, C., Gauthier, S., Corbett, A., Brayne, C., Aarsland, D., Jones, E.: Alzheimer’s disease. Lancet 377, 1019–1031 (2011)

    Article  Google Scholar 

  2. Bird, T.D.: Alzheimer’s disease and other primary dementias. In: Braunwald, E., Fauci, A.S., Kasper, D.L., Hauser, S.L., Longo, D.L., Jameson, J.L. (eds.) Harrison’s Principles of Internal Medicine, pp. 2391–2399 (2001)

    Google Scholar 

  3. Jeong, J.: EEG dynamics in patients with Alzheimer’s disease. Clin. Neurophysiol. 115, 1490–1505 (2004)

    Article  Google Scholar 

  4. Haykin, S.: Communication systems. John Wiley & Sons, New York (2001)

    Google Scholar 

  5. Rioul, O., Vetterli, M.: Wavelets and Signal Processing. IEEE Signal Processing Magazine 8, 1–38 (1992)

    Google Scholar 

  6. Poza, J., Hornero, R.: Chapter 8-Time-Frequency Analysis of MEG activity in Alzheimer’s disease. Recent Advances in Biomedical Signal Processing, 122–139 (2010)

    Google Scholar 

  7. Poza, J., Hornero, R., Abásolo, D., Fernández, A., Mayo, A.: Evaluation of spectral ratio measures from spontaneous MEG recordings in patients with Alzheimer’s disease. Computer Methods and Programs in Biomedicine 90, 37–47 (2008)

    Article  Google Scholar 

  8. Jolliffe, I.T.: Principal Component Analysis, 2nd edn. Springer, Heidelberg (2002)

    MATH  Google Scholar 

  9. Williams, C., Lee, S., Fisher, R., Dickerman, L.: A comparison of statistical methods for prenatal screening for Down syndrome. Applied Stochastic Models in Business and Ind. 15, 89–101 (1999)

    Article  MATH  Google Scholar 

  10. Bishop, M.: Neural Networks for Pattern Recognition. Oxford University Press, Oxford (1995)

    MATH  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2011 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Rodrigues, P., Teixeira, J.P. (2011). Artificial Neural Networks in the Discrimination of Alzheimer’s Disease. In: Cruz-Cunha, M.M., Varajão, J., Powell, P., Martinho, R. (eds) ENTERprise Information Systems. CENTERIS 2011. Communications in Computer and Information Science, vol 221. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-24352-3_29

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-24352-3_29

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-24351-6

  • Online ISBN: 978-3-642-24352-3

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics