Zusammenfassung
Die Alzheimer-Krankheit ist die häufigste geriatrische Krankheit. 5% der über 65-Jährigen leiden daran. Diese Zahl steigt rapide mit dem Lebensalter an, und bei den über 80-Jährigen sind es schon über 10 bis 20%. Allerdings kann die Krankheit schon bei 35-Jährigen beginnen.
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Literatur
American Psychiatric Association (1995) 148th Annual Meeting. Topic 8: Organic Mental Disorders
Ballard CG (2002) Advances in the Treatment of Alzheimer’s Disease: Benefit of Dual Cholinesterase Inhibition. Eur Neurol 47:64–70
Bloom FE, Kupfer DJ (eds) (1995) Psychopharmacology. The Fourth Generation in Progress. Geriatric Disorders: 1361–1479; Raven, NY
Bullock R, Cameron A (2002) Rivastigmine for the Treatment of Dementia and Visual Hallucinations Associated with Parkinson’s Disease: A Case Series. Current Medical Research and Opinions 18(5):258–264
Chen P, Ratcliff G, Belle SH et al (2001) Patterns of Cognitive Decline in Presymptomatic Alzheimer Disease. Arch Gen Psychiatry 58:853–860
Clark R, Goate A (1993) Molecular genetics of Alzheimer’s disease. Arch Neurol 50:1164–1172
Cohen RM, Weingartner HW, Smallberg A, Pickar D, Murphy DL (1982) Effort and cognition in depression. Arch Gen Psychiatry 39:593–597
Collis A, Maruff P, Shafiq-Antonacci R et al (2001) Memory decline in healthy older people. Implication for identifying mild cognitive impairment. Neurology 56:1533–1538
Danyscz W, Parsons CG, Möbius HJ et al (2000) Neuroprotective and Symptomatological Action of Memantine Relevant for Alzheimer’s Disease — Unified Glutamatergic Hypothesis on the Mechanism of Action (1999) Neurotoxicity Research 2:85–97
Davis KL, Thal LJ, Gamzu E et al (1992) Tacrine in patients with Alzheimer’s disease: a double blind placebo controlled multicenter study. N Engl J Med 327:1374–1379
De Leon MJ (1999) An Atlas of Alzheimer’s Disease. The Encyclopedia of Visual Medicine Series. The Parthenon Publishing Group, New York London
Erkinjuntti T, Skoog I, Lane R, Andrews C (2002) Rivastigmine in patients with Alzheimer’s disease and concurrent hypertension. IJCP 56(10):791–796
Erkinjuntti T, Kurz A, Gauthier S et al (2002) Efficacy of galantamine in probable vascular dementia and Alzheimer’s disease combined with cerebrovascular disease: a randomised trial. Lancet 359:1283–1290
Feldman H, Gauthie S, Hecker J et al (2001) A 24 week, randomized double blind study of donepezil in moderate to severe Alzheimer’ disease. Neurology 57:613–620
Freeman TW, Clothier JL, Pazzaglia P et al (1992) A Double-blind Comparison of Valproate and Lithium in the Treatment of Acute Mania. Am J Psychiatry 149:108–111
Herrmann N (2001) Recommendations for the management of the behavioral and psychological symptoms of dementia. Can J Neurol Sci 28(suppl l):96–107
Hitzenberger G, Rameis H, Manigley C (1998) Pharmacological Properties of Piracetam. CNS Drugs 9(suppl l):19–27
Jackson G (ed) (2002) Cholinesterase inhibitors: relating pharmacological properties to clinical profiles. Int J Clin Practice, Suppl 127
MacLean LE, Collins CC, Byrne EJ (2001) Dementia with Lewy bodies treated with rivastigmine. Effects on cognition, neuropsychiatric symptoms and sleep. Int Psychogeriatr 13:277–288
Mega MS (2002) Differential Diagnosis of Dementia: Clinical Examination and Laboratory Assessment. http://www.medscape.com/viewarticle/439364_print
Mohs RC (1991) Assessment of cognitive symptoms in clinical studies of antidementia drugs (Homma A. trans). Jpn J Geriatr Psychiatry 2:1195–1201
Morris JC, Storandt M, Miller P et al (2001) Mild cognitive impairment represents early stage Alzheimer’s disease. Arch Neurol 58:397–405
Morris JC (2002) Is Mild Cognitive Impairment Simply Incipient Alzheimer’s Disease? 54th Annual Meeting Denver, April 13-20, 2002 2BS.005 Education Program
Nigel H, Greig NH et al (2001) A New Therapeutic Target in Alzheimer’s Disease Treatment: Attention to Butyrylcholinesterase. Current Medical Research and Opinion 17, no 3
Prasher VP, Huxley A, Haque MS (2002) A 24 week, double blind placebo controlled trial of donepezil in patients with Down syndrome and Alzheimer’s disease. Pilot study. Int J Geriatr Psychiatry 17:270–278
Pierpaoli W, Regelson W, Fabris N (eds) (1994) The Aging Clock. Ann NY Acad Sci 719
Rapoport SI, Grady CL (1993) Parametric in vivo brain imaging during activation to examine pathological mechanisms of functional failure in Alzheimer’s disease. J Neurosci 70:39–56
Reisberg B, Finkel S, Overall J et al (2001) The Alzheimer’s Disease Activities of Daily Living International Scale (ADL-IS). Int Psychogeriatr 13:163–181
Sisodia SS, Koo EH, Beyreuther K, Unterbeck A, Price DL (1990) Evidence that β-amyloid protein in Alzheimer’s disease is not derived by normal processing. Science 248:492–495
Tariot P (2001) Current status and new developments with galantamine in the treatment of Alzheimer’s disease. Expert Opin Pharmacother 2(12):2027–2049
Venneri A, Shanks MF, Staff RT et al (2002) Cerebral blood flow and cognitive responses to rivastigmine treatment in Alzheimer’s disease: Cognitive Neuroscience and Neuropsychology 13(l):83–87
Winblad B, Poritis N (1999) Memantine bei schwerer Demenz. Ergebnisse der M-BEST-Studie. Int J Geriat Psychiatry 14:135–146
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Schmitz, M. (2004). Geriatrisch bedeutsame Substanzen. In: 1 × 1 der Psychopharmaka. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-7985-1927-5_5
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DOI: https://doi.org/10.1007/978-3-7985-1927-5_5
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