Abstract
Pediatric medicine widely uses bone age determination to assess skeletal maturity and identify developmental disorders early. However, manual assessment methods are subjective and lack consistency. To address this, we suggest using image preprocessing to isolate vital areas in hand X-rays and enhance features. We then enhance the Inception-V4 model to extract features from these images, integrating gender as a crucial reference. Our model, validated on a large dataset, demonstrates superior bone age prediction compared to prior methods. These automated models offer precise and reliable tools for clinical assessments, showing significant potential for practical application.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Alblwi, A., Baksh, M., Barner, K.E.: Bone age assessment based on salient object segmentation. In: 2021 IEEE International Conference on Imaging Systems and Techniques (IST), pp. 1–5. IEEE (2021)
Brian Shaler, DanGill, M.M.M.P.W.C.: Carvana image masking challenge (2017). https://kaggle.com/competitions/carvana-image-masking-challenge
Ding, L., Zhao, K., Zhang, X., Wang, X., Zhang, J.: A lightweight u-net architecture multi-scale convolutional network for pediatric hand bone segmentation in x-ray image. IEEE Access 7, 68436–68445 (2019)
Garn, S.M.: Radiographic atlas of skeletal development of the hand and wrist. Am. J. Hum. Genet. 11(3), 282 (1959)
Giordano, D., Leonardi, R., Maiorana, F., Scarciofalo, G., Spampinato, C.: Epiphysis and metaphysis extraction and classification by adaptive thresholding and dog filtering for automated skeletal bone age analysis. In: 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, pp. 6551–6556. IEEE (2007)
Halabi, S.S., et al.: The RSNA pediatric bone age machine learning challenge. Radiology 290(2), 498–503 (2019)
King, D.G., et al.: Reproducibility of bone ages when performed by radiology registrars: an audit of tanner and Whitehouse ii versus greulich and pyle methods. Br. J. Radiol. 67, 801 (1994)
LeCun, Y., Bottou, L., Bengio, Y., Haffner, P.: Gradient-based learning applied to document recognition. Proc. IEEE 86(11), 2278–2324 (1998)
Lv, Y., Wang, J., Wu, W., Pan, Y.: Performance comparison of deep learning methods on hand bone segmentation and bone age assessment. In: 2022 International Conference on Culture-Oriented Science and Technology (CoST), pp. 375–380. IEEE (2022)
Malina, R.M., Beunen, G.P.: Assessment of skeletal maturity and prediction of adult height (TW3 method) (2002)
Pietka, E., Gertych, A., Pospiech, S., Cao, F., Huang, H., Gilsanz, V.: Computer-assisted bone age assessment: image preprocessing and epiphyseal/metaphyseal ROI extraction. IEEE Trans. Med. Imaging 20(8), 715–729 (2001)
Redmon, J., Divvala, S., Girshick, R., Farhadi, A.: You only look once: unified, real-time object detection. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 779–788 (2016)
Ronneberger, O., Fischer, P., Brox, T.: U-Net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28
Szegedy, C., Ioffe, S., Vanhoucke, V., Alemi, A.: Inception-v4, inception-resnet and the impact of residual connections on learning. In: Proceedings of the AAAI Conference on Artificial Intelligence, vol. 31 (2017)
Van Steenkiste, T., et al.: Automated assessment of bone age using deep learning and gaussian process regression. In: 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), pp. 674–677. IEEE (2018)
Wu, E., et al.: Residual attention based network for hand bone age assessment. In: 2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019), pp. 1158–1161. IEEE (2019)
Xu, X., Xu, H., Li, Z.: Automated bone age assessment: a new three-stage assessment method from coarse to fine. In: Healthcare, vol. 10, p. 2170. MDPI (2022)
Zuiderveld, K.: Contrast limited adaptive histogram equalization. Graphics gems pp. 474–485 (1994)
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2024 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
About this paper
Cite this paper
Hsu, FC., Tsai, MC., Hsieh, SY. (2024). Automated Pediatric Bone Age Assessment Using Convolutional Neural Networks. In: Lee, CY., Lin, CL., Chang, HT. (eds) Technologies and Applications of Artificial Intelligence. TAAI 2023. Communications in Computer and Information Science, vol 2075. Springer, Singapore. https://doi.org/10.1007/978-981-97-1714-9_19
Download citation
DOI: https://doi.org/10.1007/978-981-97-1714-9_19
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-97-1713-2
Online ISBN: 978-981-97-1714-9
eBook Packages: Computer ScienceComputer Science (R0)