Abstract
Near-infrared spectroscopy (NIRS) is a continuous and noninvasive technology that measures regional tissue oxygen saturation (rSO2). A new 4-wavelength generation of NIRS monitors is now available. We aimed to compare peripheral somatic rSO2 values given by the 4-wavelength EQUANOX™ 7600 device (Nonin Medical Inc., Plymouth, Mn) and O3™ device (Masimo Corporation, Irvine, CA). Twenty adult patients scheduled for conventional elective cardiac surgery with cardiopulmonary bypass over a 4-month period were included after local Ethics Committee approval. For each patient, 2 NIRS sensors (EQUANOX and O3) were placed over the medial part of the forearm. Thirteen couples of measurements were performed at predefined intraoperative time points. We compared 260 couples of absolute intraoperative rSO2 values. No significant difference was found between both monitors: EQUANOX median rSO2 60% (95% CI 57–62) versus O3 median rSO2 62% (95% CI 61–64), P = 0.103. Bias was 4.0% and limits of agreement were ±26.3%. Significant correlations were evidenced between EQUANOX and O3 rSO2 absolute values: rho = 0.758 (95% CI 0.701–0.806), P < 0.0001, and rSO2 percent maximum difference versus baseline: rho = 0.582 (95% CI 0.188–0.815), P = 0.007. While absolute values of rSO2 given by both devices were equivalent and well correlated, the clinical agreement is probably not acceptable, meaning that EQUANOX and O3 are not interchangeable in routine practice.
Similar content being viewed by others
Explore related subjects
Discover the latest articles, news and stories from top researchers in related subjects.References
Murkin JM, Arango M. Near-infrared spectroscopy as an index of brain and tissue oxygenation. Br J Anaesth. 2009;103(Suppl 1):i3–i13.
Bartels SA, Bezemer R, de Vries FJW, Milstein DMJ, Lima A, Cherpanath TGV, Anton Van den Meiracker H, Jasper Van Bommel J, Heger M, Karemaker JM, Ince C. Multi-site and multi-depth near-infrared spectroscopy in a model of simulated (central) hypovolemia: lower body negative pressure. Intensive Care Med. 2011;37(4):671–7.
Cole AL, Herman RA, Heimlich JB, Ahsan S, Freedman BA, Shuler MS. Ability of near infrared spectroscopy to measure oxygenation in isolated upper extremity muscle compartments. J Hand Surg. 2012;37(2):297–302.
Siegenthaler N, Giraud R, Piriou V, Bendjelid K. Near-infrared spectroscopy monitoring during cardiac surgery: a promising concept? Ann Fr Anesth Réanim. 2011;30(7–8):531–2.
Scheeren TWL. Journal of Clinical Monitoring and Computing 2015 end of year summary: tissue oxygenation and microcirculation. J Clin Monit Comput. 2016;30:141–6.
Scheeren TWL, Schober P, Schwarte LA. Monitoring tissue oxygenation by near infrared spectroscopy (NIRS): background and current applications. J Clin Monit Comput. 2012;26(4):279–87.
Fellahi J-L, Butin G, Fischer M-O, Zamparini G, Gérard J-L, Hanouz J-L. Dynamic evaluation of near-infrared peripheral oximetry in healthy volunteers: a comparison between INVOS and EQUANOX. J Crit Care. 2013;28(5):881.e1-881.e6.
Davie SN, Grocott HP. Impact of extracranial contamination on regional cerebral oxygen saturation: a comparison of three cerebral oximetry technologies. Anesthesiology. 2012;116(4):834–40.
Thielmann M, Kottenberg E, Kleinbongard P, Wendt D, Gedik N, Pasa S, Price V, Tsagakis K, Neuhäuser M, Peters J, Jakob H, Heusch G. Cardioprotective and prognostic effects of remote ischaemic preconditioning in patients undergoing coronary artery bypass surgery: a single-centre randomised, double-blind, controlled trial. Lancet Lond Engl. 2013;382(9892):597–604.
Bland JM, Altman DG. Agreement between methods of measurement with multiple observations per individual. J Biopharm Stat. 2007;17(4):571–82.
Bickler PE, Feiner JR, Rollins MD. Factors affecting the performance of 5 cerebral oximeters during hypoxia in healthy volunteers. Anesth Analg. 2013;117(4):813–23.
Redford D, Paidy S, Kashif F. Absolute and trend accuracy of a new regional oximeter in healthy volunteers during controlled hypoxia. Anesth Analg. 2014;119(6):1315–9.
Pisano A, Galdieri N, Iovino TP, Angelone M, Corcione A. Direct comparison between cerebral oximetry by INVOSTM and EQUANOXTM during cardiac surgery: a pilot study. Heart Lung Vessels. 2014;6(3):197–203.
Cournoyer A, Denault A, Cossette S, Fortier A, Daoust R, Iseppon M, Chauny JM, Notebaert E. Reproducibility, interchangeability of measures, time to measure stabilization, and reference values of two tissue oximeters in healthy volunteers. J Biomed Opt. 2016;21(9):97003.
Douds MT, Straub EJ, Kent AC, Bistrick CH, Sistino JJ. A systematic review of cerebral oxygenation-monitoring devices in cardiac surgery. Perfusion. 2014;29(6):545–52.
Steenhaut K, Lapage K, Bové T, De Hert S, Moerman A. Evaluation of different near-infrared spectroscopy technologies for assessment of tissue oxygen saturation during a vascular occlusion test. J Clin Monit Comput. 2016. doi:10.1007/s10877-016-9962-1.
Gómez H, Torres A, Polanco P, Kim HK, Zenker S, Puyana JC, Pinsky MR. Use of non-invasive NIRS during a vascular occlusion test to assess dynamic tissue O(2) saturation response. Intensive Care Med. 2008;34(9):1600–7.
Mayeur C, Campard S, Richard C, Teboul J-L. Comparison of four different vascular occlusion tests for assessing reactive hyperemia using near-infrared spectroscopy. Crit Care Med. 2011;39(4):695–701.
Fellahi J-L, Butin G, Zamparini G, Fischer M-O, Gérard J-L, Hanouz J-L. Lower limb peripheral NIRS parameters during a vascular occlusion test: an experimental study in healthy volunteers. Ann Fr Anesth Réanim. 2014;33(1):e9–e14.
Hausenloy DJ, Mwamure PK, Venugopal V, Harris J, Barnard M, Grundy E, Ashley E, Vichare S, Di Salvo C, Kolvekar S, Hayward M, Keogh B, MacAllister RJ, Yellon DM. Effect of remote ischaemic preconditioning on myocardial injury in patients undergoing coronary artery bypass graft surgery: a randomised controlled trial. Lancet Lond Engl. 2007;370(9587):575–9.
Kim MB, Ward DS, Cartwright CR, Kolano J, Chlebowski S, Henson LC. Estimation of jugular venous O2 saturation from cerebral oximetry or arterial O2 saturation during isocapnic hypoxia. J Clin Monit Comput. 2000;16(3):191–9.
Funding
The study was supported entirely by departmental sources.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that they have no conflict of interests.
Research involving human participants
As the design of the study was purely observational, waive written informed consent was authorized (local Ethics Committee). Verbal information was given to all patients.
Rights and permissions
About this article
Cite this article
Ferraris, A., Jacquet-Lagrèze, M. & Fellahi, JL. Four-wavelength near-infrared peripheral oximetry in cardiac surgery patients: a comparison between EQUANOX and O3. J Clin Monit Comput 32, 253–259 (2018). https://doi.org/10.1007/s10877-017-0025-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10877-017-0025-z