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Bare Metal Stents Versus Drug Eluting Stents: Where Do We Stand in 2015?

  • Coronary Artery Disease (D Feldman and V Voudris, Section Editors)
  • Published:
Current Treatment Options in Cardiovascular Medicine Aims and scope Submit manuscript

Opinion statement

The development of bare metal stent (BMS) was a major advancement over plain old balloon angioplasty (POBA) in the management of symptomatic coronary artery disease. BMS prevented restenosis by attenuating early arterial recoil and contraction; both seen commonly after POBA. However, the rate of clinically indicated target lesion repeat revascularization due to a process of in-stent restenosis (ISR) at 1 year remained relatively high (10 to 20 %), often due to excessive neointimal growth (Fischman et al. N Engl J Med. 331:496, 1994; Serruys et al. N Engl J Med. 331:489, 1994; Cutlip et al. J Am Coll Cardiol 40:2082, 2002). Stents with drug elution technology (DES) were developed to reduce the relatively high rate of ISR and subsequent repeat revascularization seen with BMS. Clinical trials have confirmed a reduction of as much as 50 to 70 % in target lesion revascularization by DES compared to BMS. These findings have led to the preferential use of DES in the majority of percutaneous coronary intervention (PCI). However, as DES require a longer period of dual antiplatelet therapy (DAPT) to prevent stent thrombosis, DES are not appropriate for all patients.

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Conflict of Interest

Perwaiz M. Meraj reports grants and personal fees from Abiomed Inc., grants and personal fees from Medtronic Inc., grants and personal fees from Boston Scientific Inc.

Rajiv Jauhar reports grants and personal fees from Medtronic Inc., and Abbott Inc.

Avneet Singh declares no potential conflicts of interest.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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  1. Department of Cardiology, North Shore LIJ Health System, Hofstra – North Shore LIJ School of Medicine, 300 Community Drive, Manhasset, NY, 11030, USA

    Perwaiz M. Meraj MD, FACC, FSCAI, Rajiv Jauhar MD, FACC & Avneet Singh MD, FACC

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  1. Perwaiz M. Meraj MD, FACC, FSCAI
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  2. Rajiv Jauhar MD, FACC
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Correspondence to Perwaiz M. Meraj MD, FACC, FSCAI.

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Meraj, P.M., Jauhar, R. & Singh, A. Bare Metal Stents Versus Drug Eluting Stents: Where Do We Stand in 2015?. Curr Treat Options Cardio Med 17, 39 (2015). https://doi.org/10.1007/s11936-015-0393-y

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