Location via proxy:   [ UP ]  
[Report a bug]   [Manage cookies]                
Skip to main content
Springer Nature Link
Log in

Demonstration of Microstrip Sensor for the Feasibility Study of Non-invasive Blood-Glucose Sensing

  • Short Communication
  • Published:
MAPAN Aims and scope Submit manuscript

Abstract

The present research work is the part of the feasibility study to implement non-invasive blood-glucose sensing using microwave-based sensor. The one-port microstrip patch antenna sensor developed to exhibit variation in its electromagnetic response with respect to blood-glucose level. It has been demonstrated through in vitro controlled experiment under laboratory conditions. The novel multi-parameter-based sensitivity factor termed as GlucoSense was also defined to evaluate the sensitivity of sensor towards the change in glucose concentration. It was established that there was a good correlation between sensor’s reflection properties and glucose concentration. The findings of the controlled experiment convincingly proved that the sensor has the potential to be effectively used for developing a suitable device for non-invasive blood-glucose sensing.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8

References

  1. International Diabetes Federation, IDF Diabetes Atlas. International Diabetes Federation (2019).

  2. C. T. S. Ching and P. Connolly, reverse iontophoresis: a new approach to measure blood glucose level. Asian J. Heal. Inf. Sci. 1(4) (2007) 393–410.

    Google Scholar 

  3. S. A. Weinzimer, Analysis: PENDRA: the once and future noninvasive continuous glucose monitoring device?, Diabetes Technol. Ther. 6(4) (2004) 442–444.

    Article  Google Scholar 

  4. I. Harman-Boehm, A. Gal, A. M. Raykhman, J. D. Zahn, E. Naidis, and Y. Mayzel, noninvasive glucose monitoring: a novel approach. J. Diabetes Sci. Technol. 3(2) (2009) 253–260.

    Article  Google Scholar 

  5. V. Turgul and I. Kale, Characterization of the complex permittivity of glucose/water solutions for noninvasive RF/microwave blood glucose sensing. in IEEE International Instrumentation and Measurement Technology conference proceedings (I2MTC), 2016, pp. 1–5.

  6. S. K. Garg, R. O. Potts, N. R. Ackerman, S. J. Fermi, J. A. Tamada, and H. P. Chase, Correlation of fingerstick blood glucose measurements with GlucoWatch biographer glucose results in young subjects with type 1 diabetes. Diabetes Care 22(10) (1999) 1708–1714.

    Article  Google Scholar 

  7. I. M. E. Wentholt, J. B. L. Hoekstra, A. Zwart, and J. H. DeVries, Pendra goes Dutch: lessons for the CE mark in Europe. Diabetologia 48(6) (2005) 1055–1058.

    Article  Google Scholar 

  8. A. Caduff, L. Livshits, Y. Hayashi, and Y. Feldman, cell membrane response on d-glucose studied by dielectric spectroscopy. Erythrocyte and ghost suspensions. Am. Chem. Soc. (2004) 13827–13830.

  9. A. Caduff, E. Hirt, Y. Feldman, Z. Ali, and L. Heinemann, First human experiments with a novel non-invasive, non-optical continuous glucose monitoring system. Biosens. Bioelectron. 19(3) (2003) 209–217.

    Article  Google Scholar 

  10. Satish, K. Sen, S. Malik, and Anand, Measurement of dielectric properties of ringer lactate solution with respect to D-glucose. in IEEE International Conference on Electrical, Computer and Communication Technologies (ICECCT) (2015).

  11. Satish, K. Sen, and S. Anand, Determination of glucose-dependent dielectric properties of ringer lactate using open-ended coaxial probe method. Mapan-JMSI, 31(3) (2016) 225–230.

  12. Satish, K. Sen, and S. Anand, Impedance spectroscopy of aqueous solution samples of different glucose concentrations for the exploration of non-invasive-continuous-blood-glucose-monitoring. MAPAN (2017).

  13. Satish, K. Sen, and A. Sneh, Design of Microstrip Sensor for non invasive blood glucose monitoring. in IEEE International Conference on Emerging Trends & Innovation in ICT (ICEI), Pune, India, Feb 3–5 (2017), pp. 5–8.

  14. Satish, S. Rajesh, S. Kushal, and A. Sneh, Microwave sensor for the investigation of glucose-dependent reflection properties in aqueous samples. J. Med. Engineering Technol. 43(4) (2019) 217–222.

  15. Satish, S. Kumar, Babita, T. John, and A. K. Saxena, Realization of coaxial reference air-lines as high frequency capacitance standard at CSIR-NPL. Measurement 92 (2016) 166–171.

  16. Satish, S. Kumar, Babita, T. John, and A. K. Saxena, Evaluation of air dielectric four-terminal-pair capacitance standards using resonance frequency of impedance elements. Measurement 100 (2017) 176–182.

  17. Satish, Babita, B. Khurana, S. Kumar, and A. K. Saxena, Evaluation of four-terminal-pair capacitance standards using electrical equivalent circuit model. Measurement 73 (2015) 121–126.

  18. S. Singh, S. Kumar, Babita, and T. John, Realization of four-terminal-pair capacitors as reference standards of impedance at high frequency using impedance-matrix Method. IEEE Trans. Instrum. Meas. 66(08) (2017) 2129–2135.

  19. M. Johnson, Fetal bovine serum. Mater. Methods 2 (2012).

Download references

Acknowledgements

The authors would like to acknowledge the Director, IIT Delhi, for the permission to publish the work. The authors are also grateful to the Director, CSIR-National Physical Laboratory, India, for providing the infrastructure services required to perform the reported work.

Author information

Authors and Affiliations

  1. LF, HF Impedance and DC Metrology, CSIR-National Physical Laboratory, New Delhi, India

    Satish

  2. Department of Textile and Fibre Engineering, Indian Institute of Technology, New Delhi, India

    Kushal Sen

  3. Centre for Biomedical Engineering, Indian Institute of Technology, New Delhi, India

    Sneh Anand

Authors
  1. Satish
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Kushal Sen
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Sneh Anand
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Satish.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Satish, Sen, K. & Anand, S. Demonstration of Microstrip Sensor for the Feasibility Study of Non-invasive Blood-Glucose Sensing. MAPAN 36, 193–199 (2021). https://doi.org/10.1007/s12647-020-00396-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12647-020-00396-z

Keywords

Search

Navigation