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Is any association between alternate healthy eating index (AHEI) with lipid profile and liver enzymes? A cross-sectional Study

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Journal of Diabetes & Metabolic Disorders Aims and scope Submit manuscript

Abstract

Purpose

Based on evidence, there is a significant relationship between diet quality and the chronic conditions such as dyslipidemia and liver disorders. In the current study, we investigated the relationship between alternative healthy eating index (AHEI) and some biochemical measurements (lipid profile and liver enzymes).

Methods

In this cross-sectional study, 127 hospital employees were randomly selected (of 250 screened volunteers). AHEI was estimated based on a 168 items food frequency questionnaire. The laboratory data [triglyceride (TG), total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL), alanine transaminase (ALT), aspartate transaminase (AST)] were extracted from periodic examinations. The physical activity was also estimated with international physical activity questionnaire (IPAQ).

Results

Among 127 completed data, the mean AHEI score was 47.1. There was a direct relationship between AHEI score and HDL (P = 0.02). Among the AHEI components, the score of nuts and soybeans was directly associated with HDL level (P = 0.007). There was no association between the other AHEI components and selected biomarkers.

Conclusion

Nuts and soybeans consumption—one unit per day—may increase HDL levels. More studies are needed to evaluate the diet quality with the other dietary indices.

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Data availability

The datasets used and/or analyzed during the current study are available from the corresponding author (Dr. Mohammad Hassan Entezari; entezari@hlth.mui.ac.ir), on reasonable request.

Code availability

Not defined.

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Acknowledgements

Thanks to the Faculty of Nutrition Sciences of the University of Isfahan and Isfahan Social Security Organization for supporting this study. Also thanks to the management and staff of Hazrat Fatemeh Al-Zahra Hospital who helped us in this study. This research was supported by Isfahan University of Medical Sciences, Isfahan, Iran (No. 49440). This study has not been duplicate publication or submission elsewhere.

Funding

The authors declare no support from any commercial organization for the submitted study. The authors received no financial support for the research and/or authorship of this article.

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Authors and Affiliations

  1. Department of Clinical Nutrition, School of Nutrition & Food Science, Isfahan University of Medical Sciences, Isfahan, Iran

    Shahrzad Mirashrafi

  2. Department of Clinical Nutrition, School of Nutrition & Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Hezar-Jerib Ave, P.O. Box 319, 8174673461, Isfahan, Iran

    Marzieh Kafeshani & Mohammad Hassan Entezari

  3. Department of Epidemiology and Biostatistics, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran

    Akbar Hassanzadeh

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Contributions

SM: Conceptualization, Investigation, Writing-Original Draft. MK: Data Curation, Visualization, Writing-Review and Editing. AH: Methodology, Software, Validation, Formal analysis. MHE: Resources, Project Administration, Supervision, Funding Acquisition.

Corresponding author

Correspondence to Mohammad Hassan Entezari.

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Ethical approval

The study was approved by the Ethics Committee of Isfahan University of Medical Sciences, Isfahan, Iran (Reference Number IR.MUI.RESEARCH.REC.1398.392).

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A written informed consent was obtained from the participants to confirm their voluntary participation.

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Mirashrafi, S., Kafeshani, M., Hassanzadeh, A. et al. Is any association between alternate healthy eating index (AHEI) with lipid profile and liver enzymes? A cross-sectional Study. J Diabetes Metab Disord 20, 1537–1544 (2021). https://doi.org/10.1007/s40200-021-00898-w

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  • DOI: https://doi.org/10.1007/s40200-021-00898-w

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