Abstract
A Ni-based metal-organic framework (Ni-MOF) modified electrode was fabricated for electrochemical detection of dopamine. The Ni-MOF was synthesized by ionothermal synthesis method using an ionic liquid as a template. The morphology and composition of the Ni-MOF were characterized by scanning electron microscope, X-ray diffraction, thermogravimetric analysis, and attenuated total reflection Fourier transform infrared spectroscopy. Electrochemical responses of the Ni-MOF modified electrode toward dopamine were performed using differential pulse voltammetry. The electrochemical sensing performance of the Ni-MOF modified electrode toward dopamine was improved by the introduction of ionic liquid with a wide linear range (0.2–100 μmol L−1), and a low detection limit (60 nmol L−1). Further studies indicated that the modified electrode exhibited great selectivity to dopamine in complex mixtures, and the Ni-MOF modified electrode also has excellent stability and reproducibility. Moreover, the analysis of real samples confirmed that the modified electrode has a certain reliability.
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Guillerm V, Kim D, Eubank JF, Luebke R, Liu XF, Adil K, Lah MS, Eddaoudi M (2014) A supermolecular building approach for the design and construction of metal-organic frameworks. Chem Soc Rev 43:6141–6172
Yang SJ, Kim T, Im JH, Kim YS, Jung H, Park CR (2012) MOF-derived hierarchically porous carbon with exceptional porosity and hydrogen storage capacity. Chem Mater 24:464–470
Furukawa H, Ko N, Go YB, Aratani N, Choi SB, Choi E, Yazaydin AÖ, Snurr RQ, O’Keeffe M, Kim J, Yaghi OM (2010) Ultrahigh porosity in metal-organic frameworks. Science 329:424–428
Deng H, Doonan CJ, Furukawa H, Ferreira RB, Towne J, Knobler CB, Wang B, Yaghi OM (2010) Multiple functional groups of varying ratios in metal-organic frameworks. Science 327:846–850
Camille P, Bandosz TJ (2012) Exploring the coordination chemistry of MOF-graphite oxide composites and their applications as adsorbents. Dalton Trans 41:4027–4035
Xia W, Mahmood A, Zou R, Xu Q (2015) Metal-organic frameworks and their derived nanostructures for electrochemical energy storage and conversion. Energy Environ Sci 87:1837–1866
Brouzgou A, Gorbova E, Wang Y, Jing S, Seretis A, Liang Z, Tsiakaras P (2019) Nitrogen-doped 3D hierarchical ordered mesoporous carbon supported palladium electrocatalyst for the simultaneous detection of ascorbic acid, dopamine, and glucose. Ionics 25:6061–6070
Li JR, Sculley J, Zhou HC (2012) Metal-organic frameworks for separations. Chem Rev 112:869–932
Horike S, Umeyama D, Kitagawa S (2013) Ion conductivity and transport by porous coordination polymers and metal-organic frameworks. Accounts Chem Res 46:2376–2384
Yabushita M, Li P, Bernales V, Kobayashi H, Fukuoka A, Gagliardi L, Farha OK, Katz A (2016) Unprecedented selectivity in molecular recognition of carbohydrates by a metal–organic framework. Chem Commun 52:7094–7097
Li JR, Ryan KJ, Zhou HC (2009) Selective gas adsorption and separation in metal-organic frameworks. Chem Soc Rev 38:1477–1504
Sun Y, Li Y, Wang N, Xu QQ, Xu L, Lin M (2018) Copper-based metal-organic framework for non-enzymatic electrochemical detection of glucose. Electroanal. 30:474–478
Yi FY, Chen DX, Wu MK, Han L, Jiang HL (2016) Chemical sensors based on metal-organic frameworks. Chempluschem 81:675–690
Dang W, Sun Y, Jiao H, Xu L, Lin M (2020) AuNPs-NH2/Cu-MOF modified glassy carbon electrode as enzyme-free electrochemical sensor detecting H2O2. J Electroanal Chem 856:113592
Lopa NS, Rahman MM, Ahmed F, Sutradhar SC, Ryu T, Kim W (2018) A Ni-based redox-active metal-organic framework for sensitive and non- enzymatic detection of glucose. J Electroanal Chem 822:43–49
Arul P, John SA (2018) Size controlled synthesis of Ni-MOF using polyvinylpyrrolidone: new electrode material for the trace level determination of nitrobenzene. J Electroanal Chem 829:168–176
Dai H, Chen D, Li Y, Cao P, Wang N, Lin M (2018) Voltammetric sensing of dopamine based on a nanoneedle array consisting of NiCo2S4 hollow core-shells on a nickel foam. Microchim Acta 185:157
Beitollahi H, Dourandish Z, Ganjali MR, Shaker S (2018) Voltammetric determination of dopamine in the presence of tyrosine using graphite screen-printed electrode modified with graphene quantum dots. Ionics 24:4023–4031
Wang D, Xu F, Hu J, Lin M (2017) Phytic acid/graphene oxide nanocomposites modified electrode for electrochemical sensing of dopamine. Mater Sci Eng C 71:1086–1089
Xu L, Yan S, Choi EY, Lee JY, Kwon YU (2009) Product control by halide ions of ionic liquids in the ionthermal syntheses of Ni–(H)BTC metal–organic frameworks. Chem Commun 23:3431–3433
Michael B, Devaraj M, Kathavarayan T, Pundlik RB, Duraisamy S, Sellappan S (2017) A bioinspired ionic liquid tagged cobalt-salophen complex for nonenzymatic detection of glucose. Biosens Bioelectron 91:380–387
Rao HB, Zhang ZY, Ge HW, Liu X, Zou P, Wang XX, Wang YY (2017) Enhanced amperometric sensing using a NiCo2O4/nitrogen-doped reduced graphene oxide/ionic liquid ternary composite for enzyme-free detection of glucose. New J Chem 41:3667–3676
Wang CH, Yang CH, Chang JK (2017) High-selectivity electrochemical non-enzymatic sensors based on graphene/Pd nanocomposites functionalized with designated ionic liquids. Biosens Bioelectron 89:483–488
Pamham ER, Morris RE (2006) 1-Alkyl-3-methyl imidazolium bromide ionic liquids in the ionothermal synthesis of aluminium phosphate molecular sieves. Chem Mater 18:4882–4887
Bonhote P, Dias AP, Papageorgiou N, Kalyanasundaram K, Gratzel M (1996) Hydrophobic, highly conductive ambient-temperature molten salts. Inorg Chem 35:1168–1178
Zhang YD, Lin BP, Sun Y, Zhang XQ, Yang H, Wang JC (2015) Carbon nanotubes@metal–organic frameworks as Mn-based symmetrical supercapacitor electrodes for enhanced charge storage. RSC Adv 5:58100–58106
Wang QH, Wang QX, Xu BY, Gao F, Zhao C (2018) Flower-shaped multiwalled carbon nanotubes@nickel-trimesic acid MOF composite as a high-performance cathode material for energy storage. Electrochim Acta 281:69–77
Yoshida Y, Fujie K, Lim DW, Ikeda R, Kitagawa H (2019) Superionic conduction over a wide temperature range in a metal-organic framework impregnated with ionic liquids. Angew Chem Int Ed 58:1–6
Tong M, Dong S, Wang K, Suo G (2017) A porphyrin MOF and ionic liquid biocompatible matrix for the direct electrochemistry and electrocatalysis of cytochrome c. J Electrochem Soc 164:B200–B204
Dong S, Li N, Suo G, Huang T (2013) Inorganic/organic doped carbon aerogels as biosensing materials for the detection of hydrogen peroxide. Anal Chem 85:11739–11746
Perumal M, Annadurai T, Venkatachlam R, Noel N, Vembu S (2019) Enhanced electrocatalytic activity of Ni-CNT nanocomposites for simultaneous determination of epinephrine and dopamine. Electroanalysis. 31:2387–2396
Vinoth S, Ramaraj R, Pandikumar A (2020) Facile synthesis of calcium stannate incorporated graphitic carbon nitride nanohybrid materials: a sensitive electrochemical sensor for determining dopamine. Mater Chem Phys 245:122743
Yao WQ, Guo H, Lin H, Li Q, Xue R, Wu N, Li L, Wang MY, Wu Y (2019) Simultaneous electrochemical determination of acetaminophen and dopamine based on metal-organic framework/multiwalled carbon nanotubes-Au@Ag nanocomposites. J Electrochem Soc 166:B1258–B1267
Li J, Xia JF, Zhang FF, Wang ZH, Lin QY (2018) A novel electrochemical sensor based on copper-based metal-organic framework for the determination of dopamine. J Chin Chem Soc 65:743–749
Qiu ZW, Yang T, Guo R, Jie GF, Hou WG (2019) An electrochemical ratiometric sensor based on 2D MOF nanosheet/Au/polyxanthurenic acid composite for detection of dopamine. J Electroanal Chem 835:123–129
Gao LL, Sun WJ, Yin XM, Bu R, Gao EQ (2019) Graphite paste electrodes modified with a sulfo-functionalized metal-organic framework (type MIL-101) for voltammetric sensing of dopamine. Microchim Acta 186:762
Duan CQ, Zheng JB (2019) Bimetallic MOF-based enzyme-free sensor for highly sensitive and selective detection of dopamine. J Electrochem Soc 166:B942–B947
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This work was supported by the Young Scholars Program of Shandong University.
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Huang, Z., Zhang, L., Cao, P. et al. Electrochemical sensing of dopamine using a Ni-based metal-organic framework modified electrode. Ionics 27, 1339–1345 (2021). https://doi.org/10.1007/s11581-020-03857-2
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DOI: https://doi.org/10.1007/s11581-020-03857-2