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Enterotachogram Analysis to Distinguish Irritable Bowel Syndrome from Crohn's Disease

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Abstract

Crohn's disease is often initially misdiagnosed as irritable bowel syndrome. The goal of this research was to determine if computerized auscultation (fasting enterotachogram analysis) could have a role in distinguishing between these diagnoses. Patients with irritable bowel syndrome, Crohn's disease, and a control group were enrolled in the study. The fasting sound-to-sound interval, standard deviation of the interval, sounds per minute, and percentage time involved with bowel sounds was determined by computerized enterotachogram analysis. The mean sound-to-sound interval for the Crohn's group (1232 msecs) and the controls (1706 msecs) was significantly higher than the irritable bowel group (511 msecs, P < 0.0001). We conclude that Crohn's is not characterized by a shortened interval. The high negative predictive value of the fasting enterotachogram for irritable bowel syndrome suggests that an interval greater than 740 msecs should trigger a search for an alternative diagnosis to irritable bowel. Crohn's disease should be included in that differential.

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Authors and Affiliations

  1. Western Research Company, Inc., 2127 E. Speedway, Suite 209, Tucson, Arizona, 85719

    Brian L. Craine & Cynthia J. O'Toole

  2. Department of Gastroenterology, Alameda County Medical Center (Highland Campus), 1411 E. 31 Street, Oakland, California, 94602

    Michael L. Silpa

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  1. Brian L. Craine
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  2. Michael L. Silpa
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  3. Cynthia J. O'Toole
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Craine, B.L., Silpa, M.L. & O'Toole, C.J. Enterotachogram Analysis to Distinguish Irritable Bowel Syndrome from Crohn's Disease. Dig Dis Sci 46, 1974–1979 (2001). https://doi.org/10.1023/A:1010651602095

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