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The mucosal milieu creates tolerogenic dendritic cells and TR1 and TH3 regulatory cells

Nature Immunology volume 2, pages 671–672 (2001)Cite this article

Certain types of regulatory T cells are preferentially induced at mucosal surfaces to maintain tolerance. However, the mechanisms involved in their induction are unclear. New evidence suggests DCs orchestrate this mucosal tolerogenic immune response.

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References

  1. Groux, H. et al. Nature 389, 737–742 (1997).

    Article  CAS  Google Scholar 

  2. Chen, Y., Kuchroo, V. K., Inobe, J., Hafler D. A. & Weiner, H. L. Science 265, 1237–1240 (1994).

    Article  CAS  Google Scholar 

  3. Sakaguchi, S., Sakaguchi, N., Asano, M., Itoh, M. & Toda, M. J. Immunol. 155, 1151–1164 (1995).

    CAS  PubMed  Google Scholar 

  4. Akbari, O., DeKruyff, R. H. & Umetsu, D. T. Nature Immunol. 2, 725–731 (2001).

    Article  CAS  Google Scholar 

  5. Faria, A. M. C & Weiner, H. L. Adv. Immunol. 73, 153–264 (1999).

    Article  CAS  Google Scholar 

  6. Banchereau, J. & Steinman, R. M. Nature 392, 245–252 (1998).

    Article  CAS  Google Scholar 

  7. Moser, M. & Murphy, K. M. Nature Immunol 1, 199–205 (2000).

    Article  CAS  Google Scholar 

  8. Stumbles, P. A. et al. J. Exp. Med. 188, 2019–2031 (1998).

    Article  CAS  Google Scholar 

  9. Iwasaki, A. & Kelsall, B. L. J. Exp. Med. 190, 229–239 (1999).

    Article  CAS  Google Scholar 

  10. Spaulding, D. M., Williamson, S. I., Koopman, W. J. & McGhee, J. R. J. Exp. Med. 160, 941–946 (1984).

    Article  Google Scholar 

  11. Viney, J. L., Mowat, A. M., O'Malley, J. M., Williamson, E. & Fanger, N. A. J. Immunol. 160, 5815–5825 (1998).

    CAS  PubMed  Google Scholar 

  12. Zhang,, X., Liu L., Oida, T. & Weiner, H. L. Faseb J. 14, 1198 (2000).

    Article  Google Scholar 

  13. Haneda, K. et al. J. Immunol. 159, 4484–4490 (1997).

    CAS  PubMed  Google Scholar 

  14. Cohen, L. Am. J. Respir. Cell. Mol. Biol. 24, 509–512 (2001).

    Article  Google Scholar 

Download references

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  1. Harvard Medical School, Center for Neurologic Diseases, Brigham and Women's Hospital, 77 Ave Louis Pasteur, HIM 720, Boston, 02115, MA, USA

    Howard L. Weiner

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  1. Howard L. Weiner
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Weiner, H. The mucosal milieu creates tolerogenic dendritic cells and TR1 and TH3 regulatory cells. Nat Immunol 2, 671–672 (2001). https://doi.org/10.1038/90604

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