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Translational misconceptions

Misconceptions about translation — defined as the process of turning observations in the laboratory, clinic and community into interventions that improve the health of individuals — hinder efforts to close gaps and address challenges related to the translational process. This article highlights some misconceptions with the aim of improving understanding and advancing solutions.
  1. Christopher P. Austin

    1. National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA.

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“What gets us into trouble is not what we don't know. It's what we know for sure that just ain't so.” Mark Twain

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Nature Reviews Drug Discovery 20, 489-490 (2021)

doi: https://doi.org/10.1038/d41573-021-00008-8

References

  1. Austin C. P. Translating translation. Nat. Rev. Drug Discov. 17, 455–456 (2018).

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  2. Wagner, J. et al. A dynamic map for learning, communicating, navigating and improving therapeutic development. Nat. Rev. Drug Discov. 17, 150–154 (2018).

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  3. Dowden, H. & Munro, J. Trends in clinical success rates and therapeutic focus. Nat. Rev. Drug Discov. 18, 495–496 (2019).

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Competing Interests

The author declares no competing interests.

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