The Dutch healthcare system is known for its strong emphasis on primary care and a decentralized approach to healthcare delivery. This system will have to adapt in view of the ever-increasing demand and overburdened caregivers, because otherwise it will eventually be insufficient to offer patients adequate care at sustainable costs. The focus must shift from the volume and profitability of all parties involved to a collaborative model for achieving the best outcomes for patients. Rivierenland Hospital in Tiel is preparing for a shift from treating sick patients to promoting the general health and well-being of the population in the region. This “population health” approach aims to maintain the health of all citizens. This transformation to a value-based healthcare system, centered on the needs of patients, requires a complete overhaul of the current systems and its entrenched interests and practices. The regional healthcare transformation requires a digital transformation characterized by several IT implications, such as facilitating patient’s access EHR data and sharing information at patient journey level to support the partners involved in the regional care and cure for patients. The hospital is planning to categorize its patients in order to establish an information database. This will help the hospital and its regional partners to identify opportunities for regional comprehensive care solutions as part of their transition plan.