Primary PNS tumors originate in the peripheral nerves and nerve sheaths. These tumors are often '''benign''' but can sometimes be '''malignant'''. Common types of primary PNS tumors include:
* '''[[Schwannoma]]s''': Tumors arising from [[Schwann cell]]s, which produce the [[myelin sheath]] surrounding peripheral nerves. A common subtype is the '''[[vestibular schwannoma]]''' (acoustic neuroma).<ref name="NIDCD">{{cite web |url=https://www.nidcd.nih.gov/health/vestibular-schwannoma-acoustic-neuroma-and-neurofibromatosis |title=Vestibular Schwannoma (Acoustic Neuroma) and Neurofibromatosis |date=6 March 2017 |publisher=National Institute on Deafness and Other Communication Disorders |access-date=2024-06-07}}</ref>
* '''[[Neurofibroma]]s''': Benign tumors that grow on nerves, commonly associated with '''[[neurofibromatosis type I]] (NF1)'''.<ref name="NINDS" />
* '''[[Malignant peripheral nerve sheath tumor]]s''' (MPNSTs)''': Rare but aggressive cancers that arise from peripheral nerves or nerve sheath cells.<ref name="NCI-MPNST">{{cite web |title=Malignant Peripheral Nerve Sheath Tumor (MPNST) |url=https://www.cancer.gov/pediatric-adult-rare-tumor/rare-tumors/rare-soft-tissue-tumors/mpnst |website=NCI |date=22 July 2020 |access-date=2024-06-08}}</ref>
