Appalachian may refer to:
- Appalachian Mountains, a major mountain range in eastern United States and Canada
- Appalachian Trail, a hiking trail in the eastern United States
- The people of Appalachia and their culture
- Appalachian Americans, ethnic group native to Appalachia
- Appalachian English, the variety of English native to Central and Southern Appalachia
- Appalachian music
- Appalachian State University, in Boone, North Carolina