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Mir-672 microRNA precursor family: Difference between revisions

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{{short description|RNA molecule}}
{{short description|RNA molecule}}
{{Orphan|date=March 2016}}


{{Infobox rfam
{{Infobox rfam
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In molecular biology '''mir-672 microRNA''' is a short [[non-coding RNA|RNA]] molecule. [[MicroRNA]]s function to regulate the expression levels of other genes by several mechanisms.
In molecular biology '''mir-672 microRNA''' is a short [[non-coding RNA|RNA]] molecule. [[MicroRNA]]s function to regulate the expression levels of other genes by several mechanisms.


miR-672 is underexpressed in [[neuroblastoma]] cells and has been associated with cancer pathways.<ref name="pmid22244746">{{cite journal |vauthors=Liu DZ, Ander BP, Tian Y, Stamova B, Jickling GC, Davis RR, etal | title=Integrated analysis of mRNA and microRNA expression in mature neurons, neural progenitor cells and neuroblastoma cells. | journal=Gene | year= 2012 | volume= 495 | issue= 2 | pages= 120–7 | pmid=22244746 | doi=10.1016/j.gene.2011.12.041 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22244746 }}</ref> It has further been identified as one of six miRNAs significantly downregulated in [[dorsal root ganglia]] following [[sciatic nerve]] entrapment.<ref name="pmid20704709">{{cite journal |vauthors=Rau CS, Jeng JC, Jeng SF, Lu TH, Chen YC, Liliang PC, etal | title=Entrapment neuropathy results in different microRNA expression patterns from denervation injury in rats. | journal=BMC Musculoskelet Disord | year= 2010 | volume= 11 | issue= | pages= 181 | pmid=20704709 | doi=10.1186/1471-2474-11-181 | pmc=2927509 }}</ref> Additionally, miR-672 has been found to be [[sex linkage|X-linked]] and to show preferential expression in testes and ovaries.<ref name="pmid20215419">{{cite journal |vauthors=Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, etal | title=MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing. | journal=Mol Hum Reprod | year= 2010 | volume= 16 | issue= 7 | pages= 463–71 | pmid=20215419 | doi=10.1093/molehr/gaq017 | pmc=2882868 }}</ref>
miR-672 is underexpressed in [[neuroblastoma]] cells and has been associated with cancer pathways.<ref name="pmid22244746">{{cite journal |vauthors=Liu DZ, Ander BP, Tian Y, Stamova B, Jickling GC, Davis RR, etal | title=Integrated analysis of mRNA and microRNA expression in mature neurons, neural progenitor cells and neuroblastoma cells. | journal=Gene | year= 2012 | volume= 495 | issue= 2 | pages= 120–7 | pmid=22244746 | doi=10.1016/j.gene.2011.12.041 | url=https://pubmed.ncbi.nlm.nih.gov/22244746 }}</ref> It has further been identified as one of six miRNAs significantly downregulated in [[dorsal root ganglia]] following [[sciatic nerve]] entrapment.<ref name="pmid20704709">{{cite journal |vauthors=Rau CS, Jeng JC, Jeng SF, Lu TH, Chen YC, Liliang PC, etal | title=Entrapment neuropathy results in different microRNA expression patterns from denervation injury in rats. | journal=BMC Musculoskelet Disord | year= 2010 | volume= 11 | pages= 181 | pmid=20704709 | doi=10.1186/1471-2474-11-181 | pmc=2927509 | doi-access=free }}</ref> Additionally, miR-672 has been found to be [[sex linkage|X-linked]] and to show preferential expression in testes and ovaries.<ref name="pmid20215419">{{cite journal |vauthors=Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, etal | title=MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing. | journal=Mol Hum Reprod | year= 2010 | volume= 16 | issue= 7 | pages= 463–71 | pmid=20215419 | doi=10.1093/molehr/gaq017 | pmc=2882868 }}</ref>


== See also ==
== See also ==
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==References==
==References==
{{reflist}}
{{reflist}}

==Further reading==

{{Empty section|date=July 2017}}


==External links==
==External links==

Latest revision as of 13:09, 8 August 2024

mir-672
Identifiers
Symbolmir-672
RfamRF00911
miRBase familyMIPF0000391
Other data
RNA typemicroRNA
Domain(s)Eukaryota;
PDB structuresPDBe

In molecular biology mir-672 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.

miR-672 is underexpressed in neuroblastoma cells and has been associated with cancer pathways.[1] It has further been identified as one of six miRNAs significantly downregulated in dorsal root ganglia following sciatic nerve entrapment.[2] Additionally, miR-672 has been found to be X-linked and to show preferential expression in testes and ovaries.[3]

See also

[edit]

References

[edit]
  1. ^ Liu DZ, Ander BP, Tian Y, Stamova B, Jickling GC, Davis RR, et al. (2012). "Integrated analysis of mRNA and microRNA expression in mature neurons, neural progenitor cells and neuroblastoma cells". Gene. 495 (2): 120–7. doi:10.1016/j.gene.2011.12.041. PMID 22244746.
  2. ^ Rau CS, Jeng JC, Jeng SF, Lu TH, Chen YC, Liliang PC, et al. (2010). "Entrapment neuropathy results in different microRNA expression patterns from denervation injury in rats". BMC Musculoskelet Disord. 11: 181. doi:10.1186/1471-2474-11-181. PMC 2927509. PMID 20704709.
  3. ^ Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, et al. (2010). "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing". Mol Hum Reprod. 16 (7): 463–71. doi:10.1093/molehr/gaq017. PMC 2882868. PMID 20215419.
[edit]


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