Non-ossifying fibroma: Difference between revisions
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{{Infobox disease |
{{Infobox disease |
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| Name = Nonossifying fibroma |
| Name = Nonossifying fibroma |
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Revision as of 14:10, 8 September 2017
 | This article needs more reliable medical references for verification or relies too heavily on primary sources. |  |
| Non-ossifying fibroma | |
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| Specialty | Rheumatology  |
A nonossifying fibroma (also called fibroxanthoma) is a fibrous bone lesion that is usually asymptomatic and discovered as an incidental finding on x-ray. It is the most common benign bone tumor in children and adolescents. However, it is controversial whether it represents a true neoplasm or rather a developmental disorder of growing bone. Radiographically, the tumor presents as a well marginated radiolucent lesion, with a distinct multilocular appearance. These foci consist of collagen rich connective tissue, fibroblasts, histiocytes and osteoclasts. They originate from the growth plate, and are located in adjacent parts of the metaphysis and diaphysis of long bones, most often of the legs. No treatment is needed in asymptomatic patients and spontaneous remission with replacement by bone tissue is to be expected.
Multiple nonossifying fibromas occur in Jaffe-Campanacci syndrome in combination with cafe-au-lait spots, mental retardation, hypogonadism, ocular and cardiovascular abnormalities.
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