Faculty

Trevor Bedford

Affiliate Professor, Epidemiology
Affiliate Professor, Genome Sciences


Education

PhD Biology, Harvard University, 2008
BA Biological Sciences, University of Chicago, 2002

Contact


Fred Hutchinson Cancer Research Center
Box M2-C200
Arnold Building Room M1-B861
1100 Fairview Ave N
Seattle, WA 98109
WA

Bio

Trevor Bedford is an Assistant Member at the Fred Hutchinson Cancer Research Center affiliated with the Vaccine and Infectious Disease Division and with the Computational Biology Program.

Research Areas

Research Interests

Dr. Bedford works at the interface of evolution, epidemiology and immunology. His research applies computational and statistical methods to understand viral dynamics. He is interested in using pathogen sequence data to make detailed inferences of pathogen transmission patterns. Previous research has focused on understanding antigenic drift in influenza virus, geographic spread of Ebola and within-host evolution of HIV.

Recent Publications (PubMed)

Clinical and Genomic Epidemiology of Coxsackievirus A21 and Enterovirus D68 in Homeless Shelters, King County, Washington, USA, 2019-2021.
(2024 Nov)
Emerg Infect Dis 30(11): 2250-2260
Cox SN, Casto AM, Franko NM, Chow EJ, Han PD, Gamboa L, Pfau B, Xie H, Kong K, Sereewit J, Rolfes MA, Mosites E, Uyeki TM, Greninger AL, Carone M, Shim MM, Bedford T, Shendure J, Boeckh M, Englund JA, Starita LM, Roychoudhury P, Chu HY
Antigenic drift and subtype interference shape A(H3N2) epidemic dynamics in the United States.
(2024 Sep 25)
Elife 13():
Perofsky AC, Huddleston J, Hansen CL, Barnes JR, Rowe T, Xu X, Kondor R, Wentworth DE, Lewis N, Whittaker L, Ermetal B, Harvey R, Galiano M, Daniels RS, McCauley JW, Fujisaki S, Nakamura K, Kishida N, Watanabe S, Hasegawa H, Sullivan SG, Barr IG, Subbarao K, Krammer F, Bedford T, Viboud C
High-throughput sequencing-based neutralization assay reveals how repeated vaccinations impact titers to recent human H1N1 influenza strains.
(2024 Oct 22)
J Virol 98(10): e0068924
Loes AN, Tarabi RAL, Huddleston J, Touyon L, Wong SS, Cheng SMS, Leung NHL, Hannon WW, Bedford T, Cobey S, Cowling BJ, Bloom JD
Timely vaccine strain selection and genomic surveillance improves evolutionary forecast accuracy of seasonal influenza A/H3N2.
(2024 Sep 13)
medRxiv
Huddleston J, Bedford T
Author Correction: Positive selection underlies repeated knockout of ORF8 in SARS-CoV-2 evolution.
(2024 Sep 18)
Nat Commun 15(1): 8199
Wagner C, Kistler KE, Perchetti GA, Baker N, Frisbie LA, Torres LM, Aragona F, Yun C, Figgins M, Greninger AL, Cox A, Oltean HN, Roychoudhury P, Bedford T
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