Fibronektina

FN1
Egitura erabilgarri
PDB	Ortologoaren bilaketa: H0Y7Z1%20or%20B7ZLE5 PDBe H0Y7Z1,B7ZLE5 RCSB
PDB ID kodeen zerrenda
	1E88, 1E8B, 1FBR, 1FNA, 1FNF, 1FNH, 1J8K, 1O9A, 1OWW, 1Q38, 1QGB, 1QO6, 1TTF, 1TTG, 2CG6, 2CG7, 2CK2, 2CKU, 2EC3, 2FN2, 2FNB, 2GEE, 2H41, 2H45, 2HA1, 2OCF, 2RKY, 2RKZ, 2RL0, 3CAL, 3EJH, 3GXE, 3M7P, 3MQL, 3R8Q, 3ZRZ, 4GH7, 4JE4, 4JEG, 4LXO, 4MMX, 4MMY, 4MMZ, 4PZ5, 2N1K, 5DC4, 5DC0, 5DC9, 3T1W
Identifikatzaileak
Aliasak	FN1 (HUGO), CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF, fibronectin 1, SMDCF
Kanpoko IDak	OMIM: 135600 MGI: 95566 HomoloGene: 1533 GeneCards: FN1 OMA: FN1 - orthologs
Genetikoki lotutako gaixotasunak
	spondylometaphyseal dysplasia, 'corner fracture' type
Genearen kokapena (Giza)
Kr.	Kromosoma 2 (gizakia)
Amaiera	215.436.073 bp
Genearen kokapena (Sagua)
Kr.	Kromosoma 1 (sagua)
Amaiera	71.692.359 bp
RNA adierazpena eredua
	Gehien adierazita
	diartrosia; ; right coronary artery ; ; Dezidua; ; Descending thoracic aorta ; ; synovial membrane ; ; ascending aorta ; ; Berna-hezur; ; tendon of biceps brachii ; ; stromal cell of endometrium ; ; left coronary artery ;
	Gehien adierazita
	Kalota; ; stroma of bone marrow ; ; tunica media of zone of aorta ; ; Zilbor-heste; ; left lung lobe ; ; Orkatila; ; tail of embryo ; ; tibiofemoral joint ; ; endothelial cell of lymphatic vessel ; ; atrio;
	Erreferentziazko adierazpen datu gehiago
	; ; ; ;
	Erreferentziazko adierazpen datu gehiago
Gene ontologia
Funtzio molekularra	heparin binding ; collagen binding ; integrin binding ; proteina lotura ; identical protein binding ; peptidase activator activity ; protease binding ;
Zelularen osagaia	blood microparticle ; Zelula kanpoko matrize ; Fibrinogeno ; zelulaz kanpoko eremu ; basement membrane ; apical plasma membrane ; extracellular exosome ; platelet alpha granule lumen ; endoplasmic reticulum-Golgi intermediate compartment ; extracellular fluid ;
Prozesu biologikoa	regulation of protein phosphorylation ; calcium-independent cell-matrix adhesion ; endodermal cell differentiation ; positive regulation of fibroblast proliferation ; positive regulation of substrate-dependent cell migration, cell attachment to substrate ; platelet degranulation ; extracellular matrix disassembly ; orbaintze ; positive regulation of peptidase activity ; peptide cross-linking ; Atxikipen zelular ; positive regulation of gene expression ; acute-phase response ; angiogenesis ; positive regulation of cell population proliferation ; regulation of cell shape ; regulation of ERK1 and ERK2 cascade ; cell-substrate junction assembly ; substrate adhesion-dependent cell spreading ; integrin activation ; positive regulation of axon extension ; cell-matrix adhesion ; leukocyte migration ; response to wounding ; extracellular matrix organization ;
	Iturburuak:Amigo / QuickGO
Ortologoak
	2335
	14268
	ENSG00000115414
	ENSMUSG00000026193
	P02751
	P11276
	NM_001306129; NM_001306130; NM_001306131; NM_001306132; NM_002026; NM_054034; NM_212474; NM_212475; NM_212476; NM_212478; NM_212482; NM_001365517; NM_001365518; NM_001365519; NM_001365520; NM_001365521; NM_001365522; NM_001365523; NM_001365524
	NM_001276408; NM_001276409; NM_001276410; NM_001276411; NM_001276412; NM_001276413; NM_010233
	NP_001293058; NP_001293059; NP_001293060; NP_001293061; NP_002017; NP_473375; NP_997639; NP_997641; NP_997643; NP_997647; NP_001352446; NP_001352447; NP_001352448; NP_001352449; NP_001352450; NP_001352451; NP_001352452; NP_001352453; NP_001293058.1; NP_001293059.1; NP_001293061.1
	NP_001263337; NP_001263338; NP_001263339; NP_001263340; NP_001263341; NP_001263342; NP_034363
	Wikidata
Ikusi/Editatu giza genea	Ikusi/Editatu saguaren genea

Fibronektina^[6] ornodun guztietan dagoen glukoproteina bat da. Fibronektina 440 kDa inguruko glukoproteina bat da, forma monomeriko edo dimerikoan ager daitekeena, eta animalia-ehun zelular gehienen zelula kanpoko matrizean dago. 20 isoforma ezberdin ere badaude. Fibronektina plasmatikoa deritzona, disolbagarria da eta odolean zirkulatzen du, non odolaren koagulazioa, orbaintzea eta fagozitosia areagotzen dituen.