Reaction: UK-215,364 to 1 product
- Reaction
- Reaction type
- oxidative defluorination
- Direction
- Major circulating metabolite?
- No
- Spontaneous?
- Yes
- Activity
- unknown
- References
- Roffey SJ, Cole S, Comby P, Gibson D, Jezequel SG, Nedderman AN, Smith DA, Walker DK, Wood N: The disposition of voriconazole in mouse, rat, rabbit, guinea pig, dog, and human. Drug Metab Dispos. 2003 Jun;31(6):731-41. [Article]
- Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [Article]
- Comments
- Not Available
- Enzymes
- Not Available